Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 3/20 | 0.41 |
| ▸ | EDNRB | P24530 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4767073 | 0.98 | EDNRA (0.41) | EDNRAEDNRB | |
| SCHEMBL4773521 | 0.97 | EDNRA (0.42) | EDNRAEDNRB | |
| SCHEMBL4771828 | 0.91 | EDNRA (0.40) | EDNRAEDNRB | |
| SCHEMBL6540874 | 0.91 | EDNRA (0.40) | EDNRAEDNRB | |
| SCHEMBL27541656 | 0.91 | NPSR1 (0.39) | EDNRAEDNRBNPSR1 | |
| SCHEMBL27542953 | 0.89 | EDNRA (0.38) | EDNRAEDNRBNPSR1 | |
| SCHEMBL4769995 | 0.88 | EDNRA (0.43) | EDNRAEDNRB | |
| SCHEMBL5531581 | 0.88 | EDNRA (0.45) | EDNRAEDNRB | |
| SCHEMBL4769166 | 0.87 | EDNRA (0.44) | EDNRAEDNRB | |
| SCHEMBL14414785 | 0.87 | EDNRA (0.38) | EDNRAEDNRBNPSR1OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1741713-A2 | Biphenyl sulfonamides as dual angiotensin endothelin receptor antagonists | Bristol-Myers Squibb Company (US) | 2007-01-10 | — | — | EP | disclosed |