Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 9/20 | 0.57 |
| ▸ | PPARG | P37231 | 9/20 | 0.41 |
| ▸ | PPARA | Q07869 | 8/20 | 0.41 |
| ▸ | PPARD | Q03181 | 6/20 | 0.40 |
| ▸ | BCL2 | P10415 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.38 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1997237 | 0.83 | GRM2 (0.71) | GRM2PPARGPPARAPPARDBCL2 | |
| SCHEMBL1995238 | 0.82 | GRM2 (0.68) | GRM2PPARGPPARAPPARDBCL2 | |
| SCHEMBL1997138 | 0.79 | GRM2 (0.65) | GRM2PPARGPPARAPPARD | |
| SCHEMBL1997576 | 0.78 | GRM2 (0.60) | GRM2PPARGPPARAPPARD | |
| SCHEMBL1996315 | 0.77 | GRM2 (0.65) | GRM2PPARGPPARAPPARD | |
| SCHEMBL1993438 | 0.76 | GRM2 (0.61) | GRM2PPARGPPARAPPARD | |
| SCHEMBL1998937 | 0.74 | GRM2 (0.66) | GRM2PPARGPPARAPPARD | |
| SCHEMBL5533088 | 0.72 | GRM2 (0.43) | GRM2PPARGPPARAPPARD | |
| SCHEMBL1996029 | 0.72 | GRM2 (1.00) | GRM2 | |
| SCHEMBL12611065 | 0.71 | GRM2 (0.55) | GRM2PPARGPPARAPPARDBCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1855670-A2 | BENZAZOLE POTENTIATORS OF METABOTROPIC GLUTAMATE RECEPTORS | Merck & Co., Inc. (US) | 2007-11-21 | — | — | EP | claimed |
| WO-2006091496-A2 | BENZAZOLE POTENTIATORS OF METABOTROPIC GLUTAMATE RECEPTORS | MERCK & CO., INC. (US) | 2006-08-31 | — | — | WO | claimed |