⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14865320 | 1.00 | — | — | |
| SCHEMBL9654395 | 1.00 | — | — | |
| SCHEMBL6725633 | 1.00 | — | — | |
| SCHEMBL6439560 | 0.87 | SLC22A6 (0.43) | — | |
| SCHEMBL6439563 | 0.87 | SLC22A6 (0.43) | — | |
| SCHEMBL13011642 | 0.82 | CACNA2D1 (0.35) | — | |
| SCHEMBL22501003 | 0.82 | CACNA2D1 (0.35) | — | |
| SCHEMBL22501001 | 0.82 | CACNA2D1 (0.35) | — | |
| SCHEMBL6725628 | 0.80 | — | — | |
| SCHEMBL15919051 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1806342-B1 | 3-CARBAMOYL-2-PYRIDONE DERIVATIVE | SHIONOGI & CO (JP) | 2013-04-17 | — | — | EP | disclosed |
| US-8367666-B2 | 3-carbamoyl-2-pyridone derivatives | SHIONOGI & CO., LTD. (JP) | 2013-02-05 | — | — | US | disclosed |
| US-20120208813-A1 | 3-CARBAMOYL-2-PYRIDONE DERIVATIVES | SHIONOGI & CO., LTD. | 2012-08-16 | — | — | US | disclosed |
| US-8178681-B2 | methyl 3-methyl-2-{[2-oxo-1-(2-oxo-ethyl)-1,2,5,6,7,8,9,10-octahydro-cycloocta[b]pyridine-3-carbonyl]-amino}-butyrate; cannabinoid receptor agonist; antiinflammatory agent, immunostimulant, analgesic; atopic dermatitis; excellent in photostability, and have excellent transdermal and oral absorbency | SHIONOGI & CO., LTD. (JP) | 2012-05-15 | — | — | US | disclosed |
| EP-0258032-B1 | PROCESSES AND INTERMEDIATES FOR N-(S-3-ALKYLHEPTANOYL)-D-GAMMA-GLUTAMYL-GLYCYL-D-ALANINE | PFIZER INC. (US) | 1992-07-29 | — | — | EP | disclosed |
| EP-0258032-A2 | Processes and intermediates for N-(S-3-alkylheptanoyl)-D-gamma-glutamyl-glycyl-D-alanine | PFIZER INC. (US) | 1988-03-02 | — | — | EP | disclosed |