Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.70 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.70 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.70 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.63 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | RHOA | P61586 | 1/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.39 |
| ▸ | GALR3 | O60755 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5537662 | 1.00 | PTGS1 (0.70) | PTGS1SLC6A2SLC6A4KCNH2MAPT | |
| SCHEMBL6010967 | 0.90 | PTGS1 (0.66) | PTGS1SLC6A2SLC6A4KCNH2MAPT | |
| SCHEMBL2091590 | 0.89 | PTGS1 (0.71) | PTGS1SLC6A2SLC6A4KCNH2MAPT | |
| SCHEMBL2091585 | 0.89 | PTGS1 (0.71) | PTGS1SLC6A2SLC6A4KCNH2MAPT | |
| SCHEMBL5541521 | 0.88 | PTGS1 (0.65) | PTGS1SLC6A2SLC6A4KCNH2MAPT | |
| SCHEMBL5541530 | 0.88 | PTGS1 (0.65) | PTGS1SLC6A2SLC6A4KCNH2MAPT | |
| SCHEMBL6010972 | 0.88 | KCNH2 (0.58) | PTGS1SLC6A2SLC6A4KCNH2MAPT | |
| SCHEMBL14562855 | 0.85 | KCNH2 (0.68) | PTGS1SLC6A2SLC6A4KCNH2MAPT | |
| SCHEMBL5547591 | 0.85 | KCNH2 (0.68) | PTGS1SLC6A2SLC6A4KCNH2MAPT | |
| SCHEMBL3466816 | 0.85 | KCNH2 (0.68) | PTGS1SLC6A2SLC6A4KCNH2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2570418-A2 | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2013-03-20 | — | — | EP | disclosed |
| EP-1555267-B1 | 2,3-DIHYDRO-6-NITROIMIDAZO[2,1-b]OXAZOLES | OTSUKA PHARMA CO LTD (JP) | 2013-01-16 | — | — | EP | disclosed |
| US-7262212-B2 | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-08-28 | — | — | US | disclosed |
| EP-1555267-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO 2,1-b OXAZOLES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-07-20 | — | — | EP | disclosed |