SCHEMBL5539337

SCHEMBL5539337

CCCCCC(=O)c1cc[c]cc1

nearest known ligand 0.65

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HSD17B3 P37058 8/20 0.65
HTR7 P34969 1/20 0.55
STS P08842 4/20 0.50
L3MBTL1 Q9Y468 3/20 0.48
MAPT P10636 2/20 0.48
LMNA P02545 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
MEN1 O00255 1/20 0.47
ALDH1A1 P00352 1/20 0.47
HTT P42858 1/20 0.47
KMT2A Q03164 1/20 0.47
ATM Q13315 1/20 0.47
THRA P10827 1/20 0.46
THRB P10828 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9564652 0.98 HSD17B3 (0.66) HSD17B3HTR7STSL3MBTL1MAPT
SCHEMBL4956948 0.98 HSD17B3 (0.66) HSD17B3HTR7STSL3MBTL1MAPT
SCHEMBL9564653 0.98 HSD17B3 (0.66) HSD17B3HTR7STSL3MBTL1MAPT
SCHEMBL9564644 0.98 HSD17B3 (0.66) HSD17B3HTR7STSL3MBTL1MAPT
SCHEMBL9564620 0.98 HSD17B3 (0.66) HSD17B3HTR7STSL3MBTL1MAPT
SCHEMBL9564629 0.98 HSD17B3 (0.66) HSD17B3HTR7STSL3MBTL1MAPT
SCHEMBL9564617 0.98 HSD17B3 (0.66) HSD17B3HTR7STSL3MBTL1MAPT
SCHEMBL9564630 0.98 HSD17B3 (0.66) HSD17B3HTR7STSL3MBTL1MAPT
SCHEMBL4611644 0.98 HSD17B3 (0.66) HSD17B3HTR7STSL3MBTL1MAPT
SCHEMBL1817717 0.98 HSD17B3 (0.66) HSD17B3HTR7STSL3MBTL1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101121694-A Water gelling agent used for forming supermolecule hydrogel and preparation method thereof UNIV HUAZHONG SCIENCE TECH (CN) 2008-02-13 CN claimed
CN-114957357-A Aminoglycoside derivatives and their use in the treatment of genetic disorders ELOXX制药有限公司 2022-08-30 CN disclosed
CN-102532162-B 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles OTSUKA PHARMA CO LTD 2015-05-27 CN disclosed
EP-2570418-A2 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles compound OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2013-03-20 EP disclosed
EP-1555267-B1 2,3-DIHYDRO-6-NITROIMIDAZO[2,1-b]OXAZOLES OTSUKA PHARMA CO LTD (JP) 2013-01-16 EP disclosed
CN-101121694-B Water gelling agent used for forming supermolecule hydrogel and preparation method thereof UNIV HUAZHONG SCIENCE TECH 2010-12-01 CN disclosed
CN-101255170-A 2,3-dihydroimidazo[2,1-b]oxazole compound OTSUKA PHARMA CO LTD (JP) 2008-09-03 CN disclosed
CN-101172981-A 2,3-dihydroimidazo[2,1-b]oxazole compound OTSUKA PHARMA CO LTD (JP) 2008-05-07 CN disclosed
CN-101121694-A Water gelling agent used for forming supermolecule hydrogel and preparation method thereof UNIV HUAZHONG SCIENCE TECH (CN) 2008-02-13 CN disclosed
CN-100366624-C 2, 3-dihydro-6-nitroimidazo [2,1-b ] * azole compounds OTSUKA PHARMA CO LTD (JP) 2008-02-06 CN disclosed
EP-0569328-A1 Bis-phosphite stabilized compositions CIBA-GEIGY AG (CH) 1993-11-10 EP disclosed
CN-1017708-B METHOD FOR PREPARATION OF PYRAZOLOTRIAZINE COMPOUNDS OTSUKA CHEMICAL CO LTD (JP) 1992-08-05 CN disclosed
US-4824834-A TREATING GOUT OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) 1989-04-25 US disclosed
EP-0269859-A2 Pyrazolotriazine compounds OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1988-06-08 EP disclosed
CN-87107217-A Method for preparation of pyrazolotriazine compounds 1988-05-11 CN disclosed
US-4619932-A CENTRAL NERVOUS SYSTEM CONTROLLERS; ANTI-SCHIZOPHRENIA AGENTS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1986-10-28 US disclosed
EP-0192167-A1 Use of thio-substitued ketones as photoinitiators MERCK PATENT GmbH (DE) 1986-08-27 EP disclosed
US-4567187-A CENTRAL NERVOUS SYSTEM OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1986-01-28 US disclosed
US-4460593-A Carbostyril derivatives, and central nervous system controlling agents containing the carbostyril derivatives OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1984-07-17 US disclosed
US-4455422-A ANTIHISTAMINES, CNS CONTROLLERS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1984-06-19 US disclosed