Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 10/20 | 0.36 |
| ▸ | CDK9 | P50750 | 10/20 | 0.36 |
| ▸ | IGF1R | P08069 | 1/20 | 0.34 |
| ▸ | CFTR | P13569 | 3/20 | 0.34 |
| ▸ | JAK2 | O60674 | 2/20 | 0.33 |
| ▸ | JAK1 | P23458 | 2/20 | 0.33 |
| ▸ | SUV39H2 | Q9H5I1 | 2/20 | 0.33 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.32 |
| ▸ | RET | P07949 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2991596 | 0.93 | IGF1R (0.36) | CCNT1CDK9IGF1R | |
| SCHEMBL2990420 | 0.92 | IGF1R (0.40) | CCNT1CDK9IGF1RJAK2 | |
| SCHEMBL2987049 | 0.92 | CCNT1 (0.43) | CCNT1CDK9IGF1R | |
| SCHEMBL2993805 | 0.91 | CCNT1 (0.39) | CCNT1CDK9IGF1R | |
| SCHEMBL2996531 | 0.88 | IGF1R (0.38) | CCNT1CDK9IGF1R | |
| SCHEMBL5532021 | 0.86 | CCNT1 (0.39) | CCNT1CDK9IGF1RCFTRSUV39H2 | |
| SCHEMBL2991814 | 0.85 | CCNT1 (0.42) | CCNT1CDK9SUV39H2 | |
| SCHEMBL2984633 | 0.83 | IGF1R (0.38) | CCNT1CDK9IGF1RJAK2 | |
| SCHEMBL1748812 | 0.82 | IGF1R (0.49) | CCNT1CDK9IGF1RJAK2 | |
| SCHEMBL2994861 | 0.81 | IGF1R (0.39) | CCNT1CDK9IGF1RJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1799691-A1 | NOVEL BIS-AZAINDOLE DERIVATIVES, PREPARATION AND PHARMACEUTICAL USE THEREOF AS KINASE INHIBITORS | Aventis Pharma S.A. (FR) | 2007-06-27 | — | — | EP | disclosed |
| WO-2006037875-A1 | NOVEL BIS-AZAINDOLE DERIVATIVES, PREPARATION AND PHARMACEUTICAL USE THEREOF AS KINASE INHIBITORS | AVENTIS PHARMA S.A. (FR) | 2006-04-13 | — | — | WO | disclosed |