Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 12/20 | 0.57 |
| ▸ | WNT3A | P56704 | 12/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | F2R | P25116 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5546771 | 0.98 | CTNNB1 (0.56) | CTNNB1WNT3ALMNAGAAHDAC3 | |
| SCHEMBL5543911 | 0.95 | CTNNB1 (0.59) | CTNNB1WNT3ALMNAGAAHDAC3 | |
| SCHEMBL2096286 | 0.88 | CTNNB1 (0.62) | CTNNB1WNT3ALMNAGAAF2R | |
| SCHEMBL30089582 | 0.84 | CTNNB1 (0.75) | CTNNB1WNT3ALMNAGAAF2R | |
| SCHEMBL5660835 | 0.84 | CTNNB1 (0.58) | CTNNB1WNT3ALMNAGAAHDAC3 | |
| SCHEMBL27629360 | 0.84 | CTNNB1 (0.57) | CTNNB1WNT3ALMNAGAAF2R | |
| SCHEMBL5851305 | 0.83 | CTNNB1 (0.60) | CTNNB1WNT3ALMNAGAAHDAC3 | |
| SCHEMBL24775562 | 0.82 | CTNNB1 (0.59) | CTNNB1WNT3ALMNAGAAHDAC3 | |
| SCHEMBL3732487 | 0.82 | CTNNB1 (0.59) | CTNNB1WNT3ALMNAGAAF2R | |
| SCHEMBL31525070 | 0.82 | CTNNB1 (0.59) | CTNNB1WNT3ALMNAGAAHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2570418-A2 | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2013-03-20 | — | — | EP | disclosed |
| EP-1555267-B1 | 2,3-DIHYDRO-6-NITROIMIDAZO[2,1-b]OXAZOLES | OTSUKA PHARMA CO LTD (JP) | 2013-01-16 | — | — | EP | disclosed |
| US-7262212-B2 | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-08-28 | — | — | US | disclosed |
| US-20060094767-A1 | 2,3-Dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-05-04 | — | — | US | disclosed |
| EP-1555267-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO 2,1-b OXAZOLES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-07-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060094767-A1 | 2,3-Dihydro-6-nitroimidazo[2,1-b]oxazoles | NR2C2, NR4A3, NR4A2 | CTNNB1 2465/4885WNT3A 3020/4885LMNA 4152/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.