Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 12/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4454287 | 0.81 | F10 (0.51) | F10MEN1KMT2AHPGDTSHR | |
| SCHEMBL4454046 | 0.81 | F10 (0.51) | F10MEN1KMT2AHPGDTSHR | |
| SCHEMBL4447292 | 0.77 | F10 (0.47) | F10MEN1KMT2AHPGDTSHR | |
| SCHEMBL4467772 | 0.75 | F10 (0.50) | F10MEN1KMT2AHPGDTSHR | |
| SCHEMBL4476981 | 0.75 | F10 (0.67) | F10MEN1KMT2ATSHRMAPT | |
| SCHEMBL4449727 | 0.74 | F10 (0.51) | F10MEN1KMT2AHPGDTSHR | |
| SCHEMBL4448125 | 0.74 | F10 (0.54) | F10 | |
| SCHEMBL4447306 | 0.73 | F10 (0.55) | F10MEN1KMT2AMAPTMAPK1 | |
| SCHEMBL4005473 | 0.73 | F10 (0.49) | F10MEN1KMT2AHPGDTSHR | |
| SCHEMBL5547980 | 0.72 | F10 (0.50) | F10MEN1KMT2AHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1608645-B1 | PYRAZOLIDINE-1,2-DICARBOXYLDIPHENYLAMIDE DERIVATIVES AS COAGULATION FACTOR XA INHIBITORS FOR THE TREATMENT OF THROMBOSES | MERCK PATENT GMBH (DE) | 2007-05-02 | — | — | EP | disclosed |