SCHEMBL5542507

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5536080	1.00	PTGS1 (0.55)	PTGS1SLC6A2SLC6A4KCNH2CACNA1C
	SCHEMBL5536070	1.00	PTGS1 (0.55)	PTGS1SLC6A2SLC6A4KCNH2CACNA1C
	SCHEMBL5539838	0.89	KCNH2 (0.53)	PTGS1SLC6A2SLC6A4KCNH2CACNA1C
	SCHEMBL5543362	0.89	KCNH2 (0.53)	PTGS1SLC6A2SLC6A4KCNH2CACNA1C
	SCHEMBL5539828	0.89	KCNH2 (0.53)	PTGS1SLC6A2SLC6A4KCNH2CACNA1C
	SCHEMBL5536438	0.89	KCNH2 (0.51)	PTGS1SLC6A2SLC6A4KCNH2CACNA1C
	SCHEMBL5536440	0.89	KCNH2 (0.51)	PTGS1SLC6A2SLC6A4KCNH2CACNA1C
	SCHEMBL56976	0.88	KCNH2 (0.70)	PTGS1SLC6A2SLC6A4KCNH2CACNA1C
	SCHEMBL56977	0.88	KCNH2 (0.70)	PTGS1SLC6A2SLC6A4KCNH2CACNA1C
	SCHEMBL5540042	0.88	KCNH2 (0.70)	PTGS1SLC6A2SLC6A4KCNH2CACNA1C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.