SCHEMBL5542652

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18513689	0.78	BRD4 (0.58)	MAOBMAOABRD4CYP19A1CYP11B1
	SCHEMBL5546557	0.76	BRD4 (0.46)	MAOBMAOABRD4CYP19A1CYP11B1
	SCHEMBL26604739	0.76	MAOB (0.54)	MAOBMAOABRD4CYP19A1CYP11B1
	SCHEMBL7211895	0.75	BRD4 (0.53)	MAOBMAOABRD4CYP19A1CYP11B1
	SCHEMBL5546054	0.74	CYP11B1 (0.39)	BRD4CYP19A1CYP11B1CYP11B2CRBN
	SCHEMBL6074738	0.74	BRD4 (0.46)	MAOBMAOABRD4CYP19A1CYP11B1
	SCHEMBL5541690	0.74	MAOB (0.54)	MAOBMAOABRD4CYP19A1CYP11B1
	SCHEMBL12559634	0.71	BRD4 (0.51)	MAOBMAOABRD4CYP19A1CYP11B1
	SCHEMBL9651009	0.71	BRD4 (0.44)	MAOBMAOABRD4CYP19A1CYP11B1
	SCHEMBL14865958	0.70	MAOB (0.63)	MAOBMAOABRD4CYP19A1CYP11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.