Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5542933 | 0.94 | GRM1 (0.42) | GRM1MEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL5542942 | 0.94 | GRM1 (0.42) | GRM1MEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL4691279 | 0.93 | GRM1 (0.38) | GRM1MEN1KMT2ACNR2L3MBTL1 | |
| SCHEMBL4692246 | 0.88 | GRM1 (0.39) | GRM1MEN1KMT2ACNR2L3MBTL1 | |
| SCHEMBL4691975 | 0.88 | GRM1 (0.36) | GRM1MEN1KMT2ACNR2L3MBTL1 | |
| SCHEMBL4691273 | 0.87 | GRM1 (0.44) | GRM1MEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL4691276 | 0.87 | GRM1 (0.44) | GRM1MEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL4689303 | 0.87 | MEN1 (0.40) | GRM1MEN1KMT2ACNR2L3MBTL1 | |
| SCHEMBL4694655 | 0.84 | MEN1 (0.38) | GRM1MEN1KMT2ACNR2ALDH1A1 | |
| SCHEMBL4692237 | 0.83 | GRM1 (0.46) | GRM1MEN1KMT2AL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7250429-B2 | Aminomethyl-substituted thiazolobenzimidazole compounds | ASTELLAS PHARMA INC. (JP) | 2007-07-31 | — | — | US | disclosed |
| EP-1486501-A1 | AMINOMETHYL-SUBSTITUTED THIAZOLOBENZIMIDAZOLE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 2004-12-15 | — | — | EP | disclosed |