Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | THRB | P10828 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | SLC22A1 | O15245 | 3/20 | 0.47 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hexane SCHEMBL9550487 | 1.00 | TSHR (0.64) | TSHRALDH1A1THRBTDP1LMNA | |
| Hexane SCHEMBL7176518 | 1.00 | TSHR (0.64) | TSHRALDH1A1THRBTDP1LMNA | |
| Hexane SCHEMBL19547603 | 1.00 | TSHR (0.64) | TSHRALDH1A1THRBTDP1LMNA | |
| Hexane SCHEMBL571199 | 1.00 | TSHR (0.64) | TSHRALDH1A1THRBTDP1LMNA | |
| Hexane SCHEMBL6576 | 1.00 | — | — | |
| Hexane SCHEMBL2818973 | 1.00 | TSHR (0.64) | TSHRALDH1A1THRBTDP1LMNA | |
| Hexane SCHEMBL5594746 | 1.00 | TSHR (0.64) | TSHRALDH1A1THRBTDP1LMNA | |
| Hexane SCHEMBL2693386 | 1.00 | TSHR (0.64) | TSHRALDH1A1THRBTDP1LMNA | |
| Hexane SCHEMBL6552198 | 1.00 | TSHR (0.64) | TSHRALDH1A1THRBTDP1LMNA | |
| Hexane SCHEMBL16897661 | 1.00 | TSHR (0.64) | TSHRALDH1A1THRBTDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2570418-A2 | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2013-03-20 | — | — | EP | disclosed |
| EP-1555267-B1 | 2,3-DIHYDRO-6-NITROIMIDAZO[2,1-b]OXAZOLES | OTSUKA PHARMA CO LTD (JP) | 2013-01-16 | — | — | EP | disclosed |
| US-7262212-B2 | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-08-28 | — | — | US | disclosed |
| US-20060094767-A1 | 2,3-Dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-05-04 | — | — | US | disclosed |
| EP-1555267-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO 2,1-b OXAZOLES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-07-20 | — | — | EP | disclosed |
| EP-0846982-B1 | Heat-developable light-sensitive material and method of forming color images | FUJI PHOTO FILM CO LTD (JP) | 2002-08-21 | — | — | EP | disclosed |
| US-6051359-A | CONTAINS DYES WHICH ARE DECOLORIZED THROUGH REACTION WITH A DECOLORIZING AGENT DURING A DEVELOPMENT PROCESS. THE DYES ARE NON-DIFFUSIBLE | FUJI PHOTO FILM CO., LTD. (JP) | 2000-04-18 | — | — | US | disclosed |
| EP-0846982-A2 | Heat-developable light-sensitive material and method of forming color images | FUJI PHOTO FILM CO., LTD. (JP) | 1998-06-10 | — | — | EP | disclosed |
| EP-0431934-A2 | Mixtures of pyramidal columnar liquid crystals and procedure for their preparation | ECP ENICHEM POLIMERI S.r.l. (IT) | 1991-06-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060094767-A1 | 2,3-Dihydro-6-nitroimidazo[2,1-b]oxazoles | NR2C2, NR4A3, NR4A2 | TSHR 319/4885ALDH1A1 355/4885THRB 488/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.