SCHEMBL5543952

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL27558743	0.91	AGXT (0.39)	AGXTMGLLGPR84FFAR1FFAR4
	SCHEMBL5535808	0.90	AGXT (0.45)	AGXTMGLLGPR84FFAR1FFAR4
	SCHEMBL5543864	0.89	AGXT (0.44)	AGXTMGLLGPR84FFAR1FFAR4
	SCHEMBL5536741	0.87	AGXT (0.42)	AGXTMGLLGPR84FFAR1FFAR4
	SCHEMBL5537092	0.87	AGXT (0.42)	AGXTMGLLGPR84FFAR1FFAR4
	SCHEMBL5534913	0.84	FFAR1 (0.48)	AGXTGPR84FFAR1GPR52NAAA
	SCHEMBL26583	0.83	CA1 (0.48)	FFAR1AKR1B1
	Benzene SCHEMBL28219713	0.83	CA1 (0.48)	FFAR1AKR1B1
	SCHEMBL5540736	0.82	AGXT (0.59)	AGXTMGLLGPR84FFAR1FFAR4
	SCHEMBL27682114	0.82	FFAR1 (0.41)	AGXTMGLLGPR84FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.