SCHEMBL5544508

SCHEMBL5544508

[c]1ccc(CC=Cc2ccccc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 2/20 0.48
IDO1 P14902 2/20 0.42
PAM P19021 1/20 0.42
HTR2A P28223 3/20 0.40
PTGER4 P35408 1/20 0.40
PTGER3 P43115 1/20 0.40
PTGER2 P43116 1/20 0.40
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
ARG2 P78540 1/20 0.38
KDM4E B2RXH2 2/20 0.37
ALDH1A1 P00352 2/20 0.37
MAPT P10636 2/20 0.37
MEN1 O00255 1/20 0.37
RECQL P46063 1/20 0.37
KMT2A Q03164 1/20 0.37
TP53 P04637 1/20 0.37
CYP3A4 P08684 1/20 0.37
ALOX15 P16050 1/20 0.37
NPC1 O15118 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5544504 1.00 MAOB (0.48) MAOBIDO1PAMHTR2APTGER4
SCHEMBL15456006 0.92 MAOB (0.54) MAOBIDO1PAMHTR2APTGER4
SCHEMBL1892917 0.85 MAOB (0.67) MAOBIDO1PAMHTR2APTGER4
SCHEMBL163963 0.85 MAOB (0.67) MAOBIDO1PAMHTR2APTGER4
SCHEMBL4256257 0.85 MAOB (0.67) MAOBIDO1PAMHTR2APTGER4
SCHEMBL6298669 0.83 MAOB (0.71) MAOBIDO1CA1CA2ARG2
Fluoride SCHEMBL28109078 0.83 MAOB (0.64) MAOBIDO1PAMHTR2APTGER4
SCHEMBL5537527 0.79 MAOB (0.43) MAOBIDO1PAMHTR2APTGER4
SCHEMBL5537530 0.79 MAOB (0.43) MAOBIDO1PAMHTR2APTGER4
SCHEMBL27590875 0.77 NAMPT (0.40) IDO1PAMHTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11781037-B2 High-durability antifogging coating film and coating composition ASAHI KASEI KABUSHIKI KAISHA (JP) 2023-10-10 US disclosed
CN-116143660-A Compound, curing agent composition, resin composition, coating composition, and resin cured product 旭化成株式会社 2023-05-23 CN disclosed
US-20230086403-A1 LAMINATE, HARD COATING FILM, AND COATING MATERIAL COMPOSITION ASAHI KASEI KABUSHIKI KAISHA (JP) 2023-03-23 US disclosed
EP-4116085-A1 LAMINATE, HARD-COAT COATING FILM, AND COATING MATERIAL COMPOSITION Asahi Kasei Kabushiki Kaisha (JP) 2023-01-11 EP disclosed
CN-111684030-B High-durability antifogging coating film and coating composition 旭化成株式会社 2022-11-01 CN disclosed
CN-115175807-A Laminate, hard coat coating film, and coating composition 旭化成株式会社 2022-10-11 CN disclosed
CN-108699392-B High-durability antifogging coating film and coating composition 旭化成株式会社 2021-11-23 CN disclosed
US-11041076-B2 Highly durable antifogging coating film and coating composition ASAHI KASEI KABUSHIKI KAISHA (JP) 2021-06-22 US disclosed
US-20210079256-A1 HIGH-DURABILITY ANTIFOGGING COATING FILM AND COATING COMPOSITION ASAHI KASEI KABUSHIKI KAISHA (JP) 2021-03-18 US disclosed
EP-3431561-B1 HIGHLY DURABLE ANTIFOGGING COATING FILM AND COATING COMPOSITION ASAHI CHEMICAL IND (JP) 2020-12-30 EP disclosed
CN-111684030-A High-durability antifogging coating film and coating composition 旭化成株式会社 2020-09-18 CN disclosed
WO-2019163918-A1 HIGH-DURABILITY ANTIFOGGING COATING FILM AND COATING COMPOSITION 旭化成株式会社 2019-08-29 WO disclosed
US-20190055410-A1 HIGHLY DURABLE ANTIFOGGING COATING FILM AND COATING COMPOSITION ASAHI KASEI KABUSHIKI KAISHA (JP) 2019-02-21 US disclosed
EP-3431561-A1 HIGHLY DURABLE ANTIFOGGING COATING FILM AND COATING COMPOSITION Asahi Kasei Kabushiki Kaisha (JP) 2019-01-23 EP disclosed
CN-108699392-A High durable antifog coating and coating composition 旭化成株式会社 2018-10-23 CN disclosed
CN-103649408-A Flameproofing agent for fibers, method for producing flame-retardant fiber, and flame-retardant fiber MATSUMOTO YUSHI SEIYAKU KK 2014-03-19 CN disclosed
EP-1555267-B1 2,3-DIHYDRO-6-NITROIMIDAZO[2,1-b]OXAZOLES OTSUKA PHARMA CO LTD (JP) 2013-01-16 EP disclosed
US-7262212-B2 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2007-08-28 US disclosed
US-20060094767-A1 2,3-Dihydro-6-nitroimidazo[2,1-b]oxazoles OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2006-05-04 US disclosed
EP-1555267-A1 2,3-DIHYDRO-6-NITROIMIDAZO 2,1-b OXAZOLES OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2005-07-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060094767-A1 2,3-Dihydro-6-nitroimidazo[2,1-b]oxazoles NR2C2, NR4A3, NR4A2 MAOB 2140/4885IDO1 3181/4885PAM 1855/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.