Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | TOP2A | P11388 | 2/20 | 0.54 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | TOP1 | P11387 | 3/20 | 0.52 |
| ▸ | GSK3B | P49841 | 3/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.48 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.47 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.47 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5549146 | 0.97 | KDM4E (0.56) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL3975715 | 0.94 | KDM4E (0.58) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL31402735 | 0.94 | KDM4E (0.58) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL30748683 | 0.93 | KDM4E (0.57) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL4914817 | 0.93 | KDM4E (0.57) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL6309165 | 0.92 | KDM4E (0.51) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL4392662 | 0.89 | KDM4E (0.58) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL3819280 | 0.88 | KDM4E (0.53) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL3809858 | 0.88 | KDM4E (0.55) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL3819196 | 0.87 | KDM4E (0.52) | KDM4EALDH1A1LMNAHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1453846-B1 | 14 OR 15 MEMBERED MACROLIDES WITH ANTIBACTERIAL ACTIVITY | GLAXO GROUP LTD (GB) | 2007-05-16 | — | — | EP | disclosed |
| US-7202221-B2 | Macrolides | GLAXO GROUP LIMITED (GB) | 2007-04-10 | — | — | US | disclosed |
| CN-1307194-C | Macrolides | GLAXO GROUP LTD (GB) | 2007-03-28 | — | — | CN | disclosed |
| US-6967205-B1 | Compounds with antibacterial and antiparasitic properties | NEW PHARMA RESEARCH SWEDEN AB (SE) | 2005-11-22 | — | — | US | disclosed |
| CN-1612888-A | Macrolides | GLAXO GROUP LTD (GB) | 2005-05-04 | — | — | CN | disclosed |
| US-20050080025-A1 | Macrolides | PLIVA D.D. (HR) | 2005-04-14 | — | — | US | disclosed |
| EP-1230235-A1 | COMPOUNDS WITH ANTIBACTERIAL AND ANTIPARASITIC PROPERTIES | New Pharma Research Sweden AB (SE) | 2002-08-14 | — | — | EP | disclosed |
| WO-2001036408-A1 | COMPOUNDS WITH ANTIBACTERIAL AND ANTIPARASITIC PROPERTIES | NEW PHARMA RESEARCH SWEDEN AB (SE) | 2001-05-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050080025-A1 | Macrolides | IL17A, CYP51A1, IL15 | KDM4E 2733/4885ALDH1A1 2889/4885LMNA 1397/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.