⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6637809 | 1.00 | — | — | |
| SCHEMBL5545207 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL29121443 | 0.97 | — | — | |
| SCHEMBL6428359 | 0.85 | PLG (0.32) | — | |
| SCHEMBL24713485 | 0.83 | — | — | |
| SCHEMBL1762443 | 0.83 | — | — | |
| SCHEMBL1577716 | 0.83 | — | — | |
| SCHEMBL1577714 | 0.83 | — | — | |
| SCHEMBL1577711 | 0.83 | — | — | |
| SCHEMBL1762444 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3452485-B1 | ARGINASE INHIBITORS AND THEIR THERAPEUTIC APPLICATIONS | ONCOARENDI THERAPEUTICS SA (PL) | 2020-09-09 | — | — | EP | disclosed |
| WO-2017191130-A2 | ARGINASE INHIBITORS AND THEIR THERAPEUTIC APPLICATIONS | ONCOARENDI THERAPEUTICS SA (PL) | 2017-11-09 | — | — | WO | disclosed |
| WO-2013030138-A1 | PYRROLOPYRAZINE KINASE INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2013-03-07 | — | — | WO | disclosed |
| US-8039675-B2 | Catalysts | JOHNSON MATTHEY PLC (GB) | 2011-10-18 | — | — | US | disclosed |
| US-20100197976-A1 | CATALYSTS | JOHNSON MATTHEY PLC (GB) | 2010-08-05 | — | — | US | disclosed |
| EP-1849792-A1 | Biphosphine ruthenium complexes with chiral diamine ligands as catalysts | Johnson Matthey PLC (GB) | 2007-10-31 | — | — | EP | disclosed |
| EP-1651657-B1 | BIPHOSPHINE RUTHENIUM COMPLEXES WITH CHIRAL DIAMINE LIGANDS AS CATALYSTS | JOHNSON MATTHEY PLC (GB) | 2007-08-22 | — | — | EP | disclosed |
| US-7230002-B2 | Dipeptidyl peptidase IV inhibitors; processes for their preparation and compositions thereof | GLENMARK PHARMACEUTICALS LTD. (IN) | 2007-06-12 | — | — | US | disclosed |
| US-20070066850-A1 | Catalysts | JOHNSON MATTHEY PLC (GB) | 2007-03-22 | — | — | US | disclosed |
| US-20050192324-A1 | Novel dipeptidyl peptidase IV inhibitors; processes for their preparation and compositions thereof | GLENMARK PHARMACEUTICALS LTD. (IN) | 2005-09-01 | — | — | US | disclosed |