Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 19/20 | 0.69 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.59 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.59 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.59 |
| ▸ | PREP | P48147 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5549129 | 1.00 | DPP4 (0.69) | DPP4DPP8DPP7DPP9PREP | |
| SCHEMBL5545248 | 1.00 | DPP4 (0.69) | DPP4DPP8DPP7DPP9PREP | |
| SCHEMBL5548769 | 0.86 | DPP4 (0.75) | DPP4DPP8DPP7DPP9 | |
| SCHEMBL5549927 | 0.86 | DPP4 (0.75) | DPP4DPP8DPP7DPP9 | |
| SCHEMBL8283315 | 0.86 | DPP4 (0.75) | DPP4DPP8DPP7DPP9 | |
| SCHEMBL5543242 | 0.86 | DPP4 (0.75) | DPP4DPP8DPP7DPP9 | |
| SCHEMBL5545212 | 0.86 | DPP4 (0.75) | DPP4DPP8DPP7DPP9 | |
| SCHEMBL5543428 | 0.86 | DPP4 (0.75) | DPP4DPP8DPP7DPP9 | |
| Hydrochloric Acid SCHEMBL5548856 | 0.85 | DPP4 (0.74) | DPP4DPP8DPP7DPP9 | |
| Hydrochloric Acid SCHEMBL5543454 | 0.85 | DPP4 (0.74) | DPP4DPP8DPP7DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7230002-B2 | Dipeptidyl peptidase IV inhibitors; processes for their preparation and compositions thereof | GLENMARK PHARMACEUTICALS LTD. (IN) | 2007-06-12 | — | — | US | claimed |
| US-20050192324-A1 | Novel dipeptidyl peptidase IV inhibitors; processes for their preparation and compositions thereof | GLENMARK PHARMACEUTICALS LTD. (IN) | 2005-09-01 | — | — | US | claimed |
| US-7230002-B2 | Dipeptidyl peptidase IV inhibitors; processes for their preparation and compositions thereof | GLENMARK PHARMACEUTICALS LTD. (IN) | 2007-06-12 | — | — | US | disclosed |
| US-7230002-B2 | Dipeptidyl peptidase IV inhibitors; processes for their preparation and compositions thereof | GLENMARK PHARMACEUTICALS LTD. (IN) | 2007-06-12 | — | — | US | disclosed |
| US-20050192324-A1 | Novel dipeptidyl peptidase IV inhibitors; processes for their preparation and compositions thereof | GLENMARK PHARMACEUTICALS LTD. (IN) | 2005-09-01 | — | — | US | disclosed |
| WO-2005075426-A1 | NOVEL DIPEPTIDYL PEPTIDASE IV INHIBITORS; PROCESSES FOR THEIR PREPARATION AND COMPOSITIONS THEREOF | GLENMARK PHARMACEUTICALS LTD. (US) | 2005-08-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050192324-A1 | Novel dipeptidyl peptidase IV inhibitors; processes for their preparation and compositions thereof | DPP4, DPP3, DPP7 | DPP4 1/4885DPP8 5/4885DPP7 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.