Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.46 |
| ▸ | HTR2B | P41595 | 10/20 | 0.46 |
| ▸ | HTR3A | P46098 | 2/20 | 0.46 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.46 |
| ▸ | HTR3B | O95264 | 1/20 | 0.46 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.46 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.46 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 9/20 | 0.43 |
| ▸ | HTR2A | P28223 | 6/20 | 0.43 |
| ▸ | CDK4 | P11802 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.37 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30185022 | 1.00 | PARP1 (0.46) | PARP1HTR2BHTR3AHTR3EHTR3B | |
| SCHEMBL30698072 | 0.81 | HTR2B (0.62) | PARP1HTR2BHTR3AHTR3EHTR3B | |
| SCHEMBL30376302 | 0.81 | HTR2B (0.62) | PARP1HTR2BHTR3AHTR3EHTR3B | |
| SCHEMBL30659847 | 0.81 | PARP1 (0.49) | PARP1HTR2BHTR3AHTR3EHTR3B | |
| SCHEMBL660471 | 0.81 | HTR2B (0.62) | PARP1HTR2BHTR3AHTR3EHTR3B | |
| Hydrochloric Acid SCHEMBL28593152 | 0.80 | HTR2B (0.60) | PARP1HTR2BHTR3AHTR3EHTR3B | |
| SCHEMBL30459956 | 0.78 | HTR2B (0.50) | PARP1HTR2BHTR3AHTR3EHTR3B | |
| SCHEMBL30352321 | 0.78 | PARP1 (0.47) | PARP1HTR2BHTR3AHTR3EHTR3B | |
| Hydrochloric Acid SCHEMBL31259770 | 0.77 | TMEM97 (0.67) | PARP1HTR2BHTR3AHTR3EHTR3B | |
| Hydrochloric Acid SCHEMBL31259784 | 0.77 | TMEM97 (0.67) | PARP1HTR2BHTR3AHTR3EHTR3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111196800-B | Method for preparing lenalidomide | 欣凯医药化工中间体（上海）有限公司 | 2022-10-11 | — | — | CN | disclosed |
| EP-2817300-A1 | SOLID FORMS OF 3-(4-NITRO-1-OXOISOINDOLIN-2-YL)PIPERIDINE-2,6-DIONE | Celgene Corporation (US) | 2014-12-31 | — | — | EP | disclosed |
| WO-2013126394-A1 | SOLID FORMS OF 3-(4-NITRO-1-OXOISOINDOLIN-2-YL)PIPERIDINE-2,6-DIONE | CELGENE CORPORATION (US) | 2013-08-29 | — | — | WO | disclosed |
| EP-1797068-A1 | PROCESSES FOR THE PREPARATION OF SUBSTITUTED 2-(2,6-DIOXOPIPERIDIN-3-YL)-1-OXOISOINDOLINES | CELGENE CORPORATION (US) | 2007-06-20 | — | — | EP | disclosed |
| WO-2006028964-A1 | PROCESSES FOR THE PREPARATION OF SUBSTITUTED 2-(2,6-DIOXOPIPERIDIN-3-YL)-1-OXOISOINDOLINES | CELGENE CORPORATION (US) | 2006-03-16 | — | — | WO | disclosed |