Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.56 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.56 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.56 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.56 |
| ▸ | RNASE1 | P07998 | 1/20 | 0.47 |
| ▸ | P2RY2 | P41231 | 6/20 | 0.46 |
| ▸ | P2RY12 | Q9H244 | 3/20 | 0.45 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.45 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.45 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.45 |
| ▸ | LGALS7; LGALS7B | P47929 | 1/20 | 0.45 |
| ▸ | P2RY6 | Q15077 | 3/20 | 0.43 |
| ▸ | P2RY14 | Q15391 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12473580 | 1.00 | MEN1 (0.58) | MEN1USP2POLBKMT2ASLC28A1 | |
| SCHEMBL30574184 | 0.94 | MEN1 (0.52) | MEN1USP2POLBKMT2ASLC28A1 | |
| SCHEMBL10098571 | 0.91 | SLC28A1 (0.53) | MEN1USP2POLBKMT2ASLC28A1 | |
| SCHEMBL12404717 | 0.91 | SLC28A1 (0.53) | MEN1USP2POLBKMT2ASLC28A1 | |
| SCHEMBL13396883 | 0.91 | SLC28A1 (0.53) | MEN1USP2POLBKMT2ASLC28A1 | |
| SCHEMBL23906728 | 0.90 | MEN1 (0.71) | MEN1USP2POLBKMT2ASLC28A1 | |
| SCHEMBL9221115 | 0.90 | MEN1 (0.71) | MEN1USP2POLBKMT2ASLC28A1 | |
| SCHEMBL19326815 | 0.90 | MEN1 (0.71) | MEN1USP2POLBKMT2ASLC28A1 | |
| SCHEMBL22992319 | 0.90 | MEN1 (0.71) | MEN1USP2POLBKMT2ASLC28A1 | |
| SCHEMBL7943170 | 0.90 | MEN1 (0.71) | MEN1USP2POLBKMT2ASLC28A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070043208-A1 | Crystal structure of erythrocyte binding domain of EBA-175 | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2007-02-22 | — | — | US | claimed |
| US-5071974-A | COMPOSITIONS AND METHODS FOR THE SYNTHESIS OF OLIGONUCLEOTIDES HAVING 5'-PHOSPHORYLATED TERMINI | AMOCO CORPORATION (US) | 1991-12-10 | — | — | US | disclosed |
| EP-0266168-A2 | Compositions and methods for the synthesis of oligonucleotides having 5'-phosphorylated termini | AMOCO CORPORATION (US) | 1988-05-04 | — | — | EP | disclosed |