Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.50 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.50 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.50 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.49 |
| ▸ | AR | P10275 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.45 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.45 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.45 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27716203 | 0.83 | NCOA1 (0.62) | CYP19A1CYP11B1CYP11B2PTGDR2AR | |
| SCHEMBL2570411 | 0.83 | AR (0.53) | CYP19A1CYP11B1CYP11B2PTGDR2AR | |
| SCHEMBL3421698 | 0.81 | AR (0.58) | CYP19A1PTGDR2ARALDH1A1SMN1; SMN2 | |
| SCHEMBL30515469 | 0.81 | AR (0.58) | CYP19A1PTGDR2ARALDH1A1SMN1; SMN2 | |
| SCHEMBL15392421 | 0.81 | NCOA1 (0.48) | CYP19A1CYP11B1CYP11B2PTGDR2AR | |
| SCHEMBL3932262 | 0.79 | AR (0.47) | CYP19A1CYP11B1ARCHEK2SLC6A4 | |
| SCHEMBL4052387 | 0.79 | CYP19A1 (0.47) | CYP19A1CYP11B1CYP11B2PTGDR2AR | |
| SCHEMBL3932316 | 0.78 | AR (0.65) | CYP19A1CYP11B1CYP11B2ARALDH1A1 | |
| SCHEMBL2707586 | 0.78 | AR (0.74) | CYP19A1ARALDH1A1L3MBTL1POLB | |
| Hydrochloric Acid SCHEMBL4599477 | 0.78 | CYP19A1 (0.46) | CYP19A1CYP11B1CYP11B2PTGDR2AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1813623-A1 | PURINENUCLEOSIDE DERIVATIVE MODIFIED IN 8-POSITION AND MEDICINAL USE THEREOF | Kissei Pharmaceutical Co., Ltd. (JP) | 2007-08-01 | — | — | EP | disclosed |