SCHEMBL5548261

SCHEMBL5548261

[CH2]CCCCc1ccccc1-c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 1/20 0.50
KMT2A Q03164 1/20 0.43
PTGER1 P34995 3/20 0.41
PTGER4 P35408 3/20 0.41
PTGER3 P43115 3/20 0.41
PTGER2 P43116 3/20 0.41
FOLH1 Q04609 1/20 0.41
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA7 P43166 1/20 0.41
CA9 Q16790 1/20 0.41
CA14 Q9ULX7 1/20 0.41
PDCD1 Q15116 1/20 0.40
CD274 Q9NZQ7 1/20 0.40
PPARA Q07869 1/20 0.38
HTR7 P34969 1/20 0.38
CYP11B1 P15538 1/20 0.38
CYP11B2 P19099 1/20 0.38
KCNA5 P22460 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5541755 0.98 DPP4 (0.48) DPP4KMT2APTGER1PTGER4PTGER3
SCHEMBL3026186 0.94 DPP4 (0.52) DPP4KMT2APTGER1PTGER4PTGER3
SCHEMBL2048620 0.88 DPP4 (0.45) DPP4KMT2APTGER1PTGER4PTGER3
SCHEMBL5538023 0.85 DPP4 (0.56) DPP4KMT2APTGER1PTGER4PTGER3
SCHEMBL12506252 0.85 DPP4 (0.60) DPP4KMT2APTGER1PTGER4PTGER3
SCHEMBL8939722 0.82 DPP4 (0.52) DPP4KMT2APTGER1PTGER4PTGER3
SCHEMBL11334269 0.82 DPP4 (0.52) DPP4KMT2APTGER1PTGER4PTGER3
SCHEMBL11333152 0.80 DPP4 (0.65) DPP4KMT2APTGER1PTGER4PTGER3
SCHEMBL2092217 0.80 FFAR1 (0.43) HTR7MC4RFFAR1FFAR4
SCHEMBL5609224 0.80 DPP4 (0.50) DPP4KMT2APTGER1PTGER4PTGER3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114072439-A Curable composition and resin composition for stereolithography comprising same 株式会社可乐丽 2022-02-18 CN disclosed
CN-113993497-A Curable composition and resin composition for stereolithography comprising same 株式会社可乐丽 2022-01-28 CN disclosed
CN-113906068-A Resin composition for stereolithography 可乐丽则武齿科株式会社 2022-01-07 CN disclosed
CN-113226247-A Resin composition for stereolithography 可乐丽则武齿科株式会社 2021-08-06 CN disclosed
EP-2570418-A2 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles compound OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2013-03-20 EP disclosed
EP-1555267-B1 2,3-DIHYDRO-6-NITROIMIDAZO[2,1-b]OXAZOLES OTSUKA PHARMA CO LTD (JP) 2013-01-16 EP disclosed
US-7262212-B2 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2007-08-28 US disclosed
US-20060094767-A1 2,3-Dihydro-6-nitroimidazo[2,1-b]oxazoles OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2006-05-04 US disclosed
EP-1555267-A1 2,3-DIHYDRO-6-NITROIMIDAZO 2,1-b OXAZOLES OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2005-07-20 EP disclosed
US-6492364-B1 Triazolo and derivatives as chemokine inhibitors TORAY INDUSTRIES, INC. (JP) 2002-12-10 US disclosed
EP-1067130-A1 TRIAZOLO DERIVATIVES AND CHEMOKINE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT TORAY INDUSTRIES, INC. (JP) 2001-01-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060094767-A1 2,3-Dihydro-6-nitroimidazo[2,1-b]oxazoles NR2C2, NR4A3, NR4A2 DPP4 3965/4885KMT2A 4267/4885PTGER1 3314/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.