Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 18/20 | 0.50 |
| ▸ | MAPK13 | O15264 | 4/20 | 0.50 |
| ▸ | MAPK12 | P53778 | 4/20 | 0.50 |
| ▸ | MAPK11 | Q15759 | 4/20 | 0.50 |
| ▸ | DDR2 | Q16832 | 3/20 | 0.49 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.47 |
| ▸ | SRC | P12931 | 1/20 | 0.47 |
| ▸ | RET | P07949 | 6/20 | 0.47 |
| ▸ | CDK8 | P49336 | 6/20 | 0.47 |
| ▸ | PDGFRA | P16234 | 5/20 | 0.47 |
| ▸ | PAK4 | O96013 | 3/20 | 0.47 |
| ▸ | MAP4K5 | Q9Y4K4 | 2/20 | 0.47 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.47 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.47 |
| ▸ | TAOK1 | Q7L7X3 | 2/20 | 0.46 |
| ▸ | PRKD3 | O94806 | 3/20 | 0.45 |
| ▸ | GSK3B | P49841 | 2/20 | 0.45 |
| ▸ | MAP4K2 | Q12851 | 2/20 | 0.45 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.45 |
| ▸ | LTK | P29376 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5542484 | 0.89 | MAPK14 (0.51) | MAPK14MAPK13MAPK12MAPK11DDR2 | |
| SCHEMBL2082254 | 0.86 | MAPK14 (0.61) | MAPK14MAPK13MAPK12MAPK11DDR2 | |
| SCHEMBL2083033 | 0.85 | MAPK14 (0.57) | MAPK14MAPK13MAPK12MAPK11DDR2 | |
| SCHEMBL2082539 | 0.84 | MAPK14 (0.62) | MAPK14MAPK13MAPK12MAPK11DDR2 | |
| SCHEMBL2083384 | 0.82 | MAPK14 (0.54) | MAPK14MAPK13MAPK12MAPK11DDR2 | |
| SCHEMBL2081519 | 0.80 | MAPK14 (0.61) | MAPK14MAPK13MAPK12MAPK11DDR2 | |
| SCHEMBL2085279 | 0.79 | MAPK14 (0.68) | MAPK14MAPK13MAPK12MAPK11DDR2 | |
| SCHEMBL2081569 | 0.78 | MAPK14 (0.59) | MAPK14MAPK13MAPK12MAPK11DDR2 | |
| SCHEMBL2081078 | 0.78 | MAPK14 (0.49) | MAPK14MAPK13MAPK12MAPK11DDR2 | |
| SCHEMBL2085293 | 0.77 | MAPK14 (0.59) | MAPK14MAPK13MAPK12MAPK11DDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1835934-A2 | ENZYME MODULATORS AND TREATMENTS | Deciphera Pharmaceuticals, LLC (US) | 2007-09-26 | — | — | EP | claimed |
| WO-2006071940-A2 | ENZYME MODULATORS AND TREATMENTS | DECIPHERA PHARMACEUTICALS, LLC (US) | 2006-07-06 | — | — | WO | claimed |