Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GALR1 | P47211 | 4/20 | 0.48 |
| ▸ | DRD2 | P14416 | 4/20 | 0.44 |
| ▸ | BCL6 | P41182 | 1/20 | 0.44 |
| ▸ | GALR2 | O43603 | 3/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | MAP3K8 | P41279 | 2/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4829485 | 0.99 | GALR1 (0.49) | GALR1DRD2BCL6GALR2CTSL | |
| SCHEMBL4839380 | 0.99 | GALR1 (0.49) | GALR1DRD2BCL6GALR2CTSL | |
| SCHEMBL4829056 | 0.99 | GALR1 (0.49) | GALR1DRD2BCL6GALR2CTSL | |
| SCHEMBL4829538 | 0.99 | GALR1 (0.49) | GALR1DRD2BCL6GALR2CTSL | |
| SCHEMBL4832620 | 0.99 | GALR1 (0.49) | GALR1DRD2BCL6GALR2CTSL | |
| Hydrochloric Acid SCHEMBL5554597 | 0.98 | GALR1 (0.48) | GALR1DRD2BCL6GALR2CTSL | |
| Hydrochloric Acid SCHEMBL4838909 | 0.98 | GALR1 (0.48) | GALR1DRD2BCL6GALR2CTSL | |
| SCHEMBL4832394 | 0.98 | GALR1 (0.47) | GALR1DRD2BCL6GALR2ABCG2 | |
| Hydrochloric Acid SCHEMBL4838564 | 0.97 | GALR1 (0.47) | GALR1DRD2BCL6GALR2CTSL | |
| SCHEMBL4832219 | 0.96 | GALR1 (0.46) | GALR1DRD2BCL6GALR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7268134-B2 | Medical devices employing triazine compounds and compositions thereof | REDDY US THERAPEUTICS, INC. (US) | 2007-09-11 | — | — | US | claimed |