SCHEMBL5551682

SCHEMBL5551682

Cc1ccc(C)c(Cc2ccc(Cc3cc(C)ccc3C)cc2)c1

nearest known ligand 0.54

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.54
CYP3A4 P08684 1/20 0.45
CYP2D6 P10635 1/20 0.45
TSHR P16473 1/20 0.45
CYP2C19 P33261 1/20 0.45
GAA P10253 1/20 0.45
SLC22A12 Q96S37 1/20 0.41
ALDH1A1 P00352 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
AMY1A P0DUB6 1/20 0.41
POLB P06746 1/20 0.41
SLC5A2 P31639 2/20 0.38
SLC5A1 P13866 1/20 0.38
PDE3B Q13370 1/20 0.38
PDE3A Q14432 1/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10675819 0.98 TAAR1 (0.52) TAAR1CYP3A4CYP2D6TSHRCYP2C19
SCHEMBL31158270 0.98 TAAR1 (0.52) TAAR1CYP3A4CYP2D6TSHRCYP2C19
SCHEMBL1738131 0.94 TAAR1 (0.48) TAAR1CYP3A4CYP2D6TSHRCYP2C19
SCHEMBL24029803 0.90 SLC5A1 (0.46) TAAR1CYP3A4CYP2D6TSHRCYP2C19
SCHEMBL9395289 0.90 TAAR1 (0.46) TAAR1CYP3A4CYP2D6TSHRCYP2C19
SCHEMBL1276089 0.89 CYP3A4 (0.57) TAAR1CYP3A4CYP2D6TSHRCYP2C19
SCHEMBL5252725 0.87 TAAR1 (0.60) TAAR1GAAALDH1A1TDP1AMY1A
SCHEMBL15682905 0.84 SLC5A2 (0.53) SLC5A2SLC5A1
SCHEMBL8094710 0.83 TAAR1 (0.47) TAAR1CYP3A4CYP2D6TSHRCYP2C19
SCHEMBL28856979 0.82 CYP3A4 (0.52) TAAR1CYP3A4CYP2D6TSHRCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9989868-B2 Photoconductor, image forming method using the same, method of manufacturing the photoconductor, and image forming apparatus RICOH COMPANY, LTD. (JP) 2018-06-05 US claimed
US-20150346613-A1 PHOTOCONDUCTOR, IMAGE FORMING METHOD USING THE SAME, METHOD OF MANUFACTURING THE PHOTOCONDUCTOR, AND IMAGE FORMING APPARATUS RICOH COMPANY, LTD. (JP) 2015-12-03 US claimed
US-9989868-B2 Photoconductor, image forming method using the same, method of manufacturing the photoconductor, and image forming apparatus RICOH COMPANY, LTD. (JP) 2018-06-05 US disclosed
US-20150346613-A1 PHOTOCONDUCTOR, IMAGE FORMING METHOD USING THE SAME, METHOD OF MANUFACTURING THE PHOTOCONDUCTOR, AND IMAGE FORMING APPARATUS RICOH COMPANY, LTD. (JP) 2015-12-03 US disclosed
US-7295802-B2 Image forming apparatus using a cleaning unit for preventing noises RICOH COMPANY, LTD (JP) 2007-11-13 US disclosed
US-20070110488-A1 IMAGE FORMING APPARATUS AND PROCESS CARTRIDE THEREFOR KABATA TOSHIYUKI 2007-05-17 US disclosed
US-7181156-B2 Image forming apparatus using a cleaning member for preventing noises and process cartridge therefor RICOH COMPANY, LTD. (JP) 2007-02-20 US disclosed
US-20050069357-A1 Image forming apparatus and process cartridge therefor RICOH COMPANY, LTD (JP) 2005-03-31 US disclosed