Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.52 |
| ▸ | SLC1A3 | P43003 | 4/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 4/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.40 |
| ▸ | RNPEP | Q9H4A4 | 4/20 | 0.37 |
| ▸ | ANPEP | P15144 | 4/20 | 0.37 |
| ▸ | DNPEP | Q9ULA0 | 2/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.33 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.33 |
| ▸ | LAP3 | P28838 | 1/20 | 0.33 |
| ▸ | CPA1 | P15085 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3056494 | 0.91 | SLC7A5 (0.57) | SLC7A5SLC1A3SLC1A2SLC1A1RNPEP | |
| SCHEMBL29112233 | 0.89 | SLC7A5 (0.47) | SLC7A5SLC1A3SLC1A2SLC1A1RNPEP | |
| SCHEMBL29112238 | 0.89 | SLC7A5 (0.47) | SLC7A5SLC1A3SLC1A2SLC1A1RNPEP | |
| SCHEMBL3381469 | 0.85 | SLC1A2 (0.46) | SLC7A5SLC1A3SLC1A2SLC1A1RNPEP | |
| SCHEMBL21049239 | 0.84 | SLC7A5 (0.42) | SLC7A5SLC1A3SLC1A2SLC1A1RNPEP | |
| SCHEMBL19858949 | 0.83 | RNPEP (0.43) | SLC7A5SLC1A3SLC1A2SLC1A1RNPEP | |
| SCHEMBL19858948 | 0.83 | RNPEP (0.43) | SLC7A5SLC1A3SLC1A2SLC1A1RNPEP | |
| SCHEMBL11196394 | 0.77 | SLC7A5 (0.39) | SLC7A5SLC1A3SLC1A2SLC1A1RNPEP | |
| SCHEMBL6122992 | 0.76 | SLC1A2 (0.50) | SLC7A5SLC1A3SLC1A2SLC1A1RNPEP | |
| SCHEMBL3503689 | 0.75 | SLC1A1 (0.34) | SLC7A5SLC1A3SLC1A2SLC1A1GRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2013619-B1 | METHODS FOR USING HUMAN EMBRYONIC STEM CELLS TO EVALUATE TOXICITY OF PHARMACEUTICAL COMPOUNDS & OTHER CHEMICALS | WISCONSIN ALUMNI RES FOUND (US) | 2017-10-11 | — | — | EP | disclosed |
| US-20140255969-A1 | REAGENTS AND METHODS FOR USING HUMAN EMBRYONIC STEM CELLS TO EVALUATE TOXICITY OF PHARMACEUTICAL COMPOUNDS AND OTHER CHEMICALS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2014-09-11 | — | — | US | disclosed |
| US-8703483-B2 | Reagents and methods for using human embryonic stem cells to evaluate toxicity of pharmaceutical compounds and other chemicals | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2014-04-22 | — | — | US | disclosed |
| US-20070248947-A1 | Reagents and Methods for Using Human Embryonic Stem Cells to Evaluate Toxicity of Pharmaceutical Compounds and Other Chemicals | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2007-10-25 | — | — | US | disclosed |