Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 18/20 | 0.53 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.47 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5552241 | 0.85 | AVPR2 (0.53) | AVPR2PDCD1CD274 | |
| Hydrochloric Acid SCHEMBL5552018 | 0.81 | PDCD1 (0.47) | AVPR2PDCD1CD274 | |
| SCHEMBL5552618 | 0.81 | AVPR2 (0.46) | AVPR2PDCD1CD274 | |
| SCHEMBL2130987 | 0.80 | AVPR2 (0.51) | AVPR2PDCD1CD274 | |
| SCHEMBL5232067 | 0.70 | AVPR2 (0.66) | AVPR2 | |
| SCHEMBL5231560 | 0.70 | AVPR2 (0.66) | AVPR2 | |
| SCHEMBL2705385 | 0.69 | AVPR2 (0.42) | AVPR2PDCD1CD274 | |
| SCHEMBL6627507 | 0.69 | AVPR2 (1.00) | AVPR2 | |
| SCHEMBL1495979 | 0.69 | EPHX2 (0.64) | AVPR2 | |
| SCHEMBL18917226 | 0.69 | AVPR2 (0.42) | AVPR2PDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781661-A2 | VASOPRESSIN V1A ANTAGONISTS | Ferring B.V. (NL) | 2007-05-09 | — | — | EP | disclosed |
| WO-2006021213-A2 | VASOPRESSIN V1A ANTAGONISTS | FERRING B.V. (NL) | 2006-03-02 | — | — | WO | disclosed |