⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1653709 | 0.81 | — | — | |
| SCHEMBL5680685 | 0.72 | — | — | |
| SCHEMBL8597412 | 0.70 | HIF1A (0.43) | — | |
| SCHEMBL8602837 | 0.70 | — | — | |
| SCHEMBL8602736 | 0.70 | — | — | |
| SCHEMBL2066715 | 0.70 | TSHR (0.62) | — | |
| Glutaral SCHEMBL836 | 0.69 | — | — | |
| SCHEMBL16816939 | 0.69 | HIF1A (0.82) | — | |
| SCHEMBL139711 | 0.69 | — | — | |
| Glutaral SCHEMBL1285455 | 0.69 | HIF1A (1.00) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1802668-B1 | METHOD OF MAKING A ZIEGLER-NATTA CATALYST | LUMMUS NOVOLEN TECHNOLOGY GMBH (DE) | 2015-01-07 | — | — | EP | disclosed |
| EP-1802668-A1 | METHOD OF MAKING A ZIEGLER-NATTA CATALYST | Novolen Technology Holdings, C.V. (NL) | 2007-07-04 | — | — | EP | disclosed |
| US-7071137-B2 | Method of making a ziegler-natta catalyst | NOVOLEN TECHNOLOGY HOLDINGS, C.V. (NL) | 2006-07-04 | — | — | US | disclosed |
| WO-2006026157-A1 | METHOD OF MAKING A ZIEGLER-NATTA CATALYST | NOVOLEN TECHNOLOGY HOLDINGS C.V. (NL) | 2006-03-09 | — | — | WO | disclosed |
| US-20060046927-A1 | Method of making a Ziegler-Natta catalyst | LUMMUS NOVOLEN TECHNOLOGY GMBH (DE) | 2006-03-02 | — | — | US | disclosed |