Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 20/20 | 0.47 |
| ▸ | OXTR | P30559 | 13/20 | 0.47 |
| ▸ | AVPR2 | P30518 | 7/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2628985 | 0.94 | AVPR1A (0.51) | AVPR1AOXTRAVPR2CHRM2CHRM4 | |
| Hydrochloric Acid SCHEMBL2130209 | 0.94 | AVPR1A (0.50) | AVPR1AOXTRAVPR2CHRM2CHRM4 | |
| SCHEMBL2131344 | 0.87 | AVPR1A (0.53) | AVPR1AOXTRAVPR2CHRM2CHRM4 | |
| SCHEMBL2703856 | 0.86 | AVPR1A (0.52) | AVPR1AOXTRAVPR2CHRM2CHRM4 | |
| SCHEMBL2704240 | 0.86 | AVPR1A (0.52) | AVPR1AOXTRAVPR2CHRM2CHRM4 | |
| SCHEMBL2413918 | 0.86 | AVPR1A (0.46) | AVPR1AOXTRAVPR2CHRM2CHRM4 | |
| Hydrochloric Acid SCHEMBL2128256 | 0.85 | AVPR1A (0.51) | AVPR1AOXTRAVPR2CHRM2CHRM4 | |
| SCHEMBL2703256 | 0.85 | AVPR1A (0.53) | AVPR1AOXTRAVPR2CHRM2CHRM4 | |
| SCHEMBL2702943 | 0.85 | AVPR1A (0.59) | AVPR1AOXTRAVPR2CHRM2CHRM4 | |
| SCHEMBL18944418 | 0.85 | AVPR1A (0.51) | AVPR1AOXTRAVPR2CHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781661-A2 | VASOPRESSIN V1A ANTAGONISTS | Ferring B.V. (NL) | 2007-05-09 | — | — | EP | disclosed |
| WO-2006021213-A2 | VASOPRESSIN V1A ANTAGONISTS | FERRING B.V. (NL) | 2006-03-02 | — | — | WO | disclosed |