SCHEMBL5552653

SCHEMBL5552653

CCCCCC[Mg]CCC=O

nearest known ligand 0.58

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.58
FAAH O00519 2/20 0.52
TRPV1 Q8NER1 2/20 0.52
ADH1B P00325 2/20 0.43
ADH1C P00326 2/20 0.43
ADH1A P07327 2/20 0.43
ADH7 P40394 2/20 0.43
EPHX1 P07099 1/20 0.43
ADH4 P08319 1/20 0.43
ALDH1A1 P00352 3/20 0.42
THRB P10828 1/20 0.36
ZDHHC20 Q5W0Z9 1/20 0.35
ZDHHC2 Q9UIJ5 1/20 0.35
DNM1 Q05193 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1652865 0.91
SCHEMBL2066715 0.81 TSHR (0.62) TSHRFAAHTRPV1ADH1BADH1C
SCHEMBL1653669 0.80
SCHEMBL6234379 0.80 TSHR (0.57) TSHREPHX1ALDH1A1THRBDNM1
SCHEMBL11041293 0.80 TSHR (0.57) TSHREPHX1ALDH1A1THRBDNM1
SCHEMBL10317806 0.80 TSHR (0.57) TSHREPHX1ALDH1A1THRBDNM1
SCHEMBL152301 0.80 TSHR (0.57) TSHREPHX1ALDH1A1THRBDNM1
SCHEMBL11570870 0.80 TSHR (0.57) TSHREPHX1ALDH1A1THRBDNM1
SCHEMBL9066881 0.80 TSHR (0.57) TSHREPHX1ALDH1A1THRBDNM1
SCHEMBL3676208 0.80 TSHR (0.57) TSHREPHX1ALDH1A1THRBDNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1802668-B1 METHOD OF MAKING A ZIEGLER-NATTA CATALYST LUMMUS NOVOLEN TECHNOLOGY GMBH (DE) 2015-01-07 EP disclosed
EP-1802668-A1 METHOD OF MAKING A ZIEGLER-NATTA CATALYST Novolen Technology Holdings, C.V. (NL) 2007-07-04 EP disclosed
US-7071137-B2 Method of making a ziegler-natta catalyst NOVOLEN TECHNOLOGY HOLDINGS, C.V. (NL) 2006-07-04 US disclosed
WO-2006026157-A1 METHOD OF MAKING A ZIEGLER-NATTA CATALYST NOVOLEN TECHNOLOGY HOLDINGS C.V. (NL) 2006-03-09 WO disclosed
US-20060046927-A1 Method of making a Ziegler-Natta catalyst LUMMUS NOVOLEN TECHNOLOGY GMBH (DE) 2006-03-02 US disclosed