Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 2/20 | 0.83 |
| ▸ | FNTB | P49356 | 2/20 | 0.83 |
| ▸ | THRB | P10828 | 1/20 | 0.83 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.83 |
| ▸ | CES1 | P23141 | 2/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.41 |
| ▸ | PPARG | P37231 | 6/20 | 0.41 |
| ▸ | PPARD | Q03181 | 6/20 | 0.41 |
| ▸ | PPARA | Q07869 | 6/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | TLR2 | O60603 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | FABP4 | P15090 | 2/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1086437 | 1.00 | FNTA (0.83) | FNTAFNTBTHRBPGGT1BCES1 | |
| SCHEMBL555289 | 1.00 | FNTA (0.83) | FNTAFNTBTHRBPGGT1BCES1 | |
| SCHEMBL554180 | 0.93 | FNTA (0.96) | FNTAFNTBTHRBPGGT1BCES1 | |
| SCHEMBL554183 | 0.93 | FNTA (0.96) | FNTAFNTBTHRBPGGT1BCES1 | |
| SCHEMBL9839280 | 0.91 | FNTA (1.00) | FNTAFNTBTHRBPGGT1BCES1 | |
| SCHEMBL30119478 | 0.91 | FNTA (1.00) | FNTAFNTBTHRBPGGT1BCES1 | |
| SCHEMBL28492286 | 0.91 | FNTA (1.00) | FNTAFNTBTHRBPGGT1BCES1 | |
| Chaetomellic Acid A SCHEMBL29394340 | 0.91 | FNTA (1.00) | FNTAFNTBTHRBPGGT1BCES1 | |
| Chaetomellic Acid C SCHEMBL6686707 | 0.91 | FNTA (1.00) | FNTAFNTBTHRBPGGT1BCES1 | |
| SCHEMBL6692451 | 0.91 | FNTA (1.00) | FNTAFNTBTHRBPGGT1BCES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 153 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220105064-A1 | CONTROLLED RELEASE PHARMACEUTICAL COMPOSITIONS COMPRISING A FUMARIC ACID ESTER | BIOGEN SWISS MFG GMBH (CH) | 2022-04-07 | — | — | US | claimed |
| US-20220079884-A1 | PHARMACEUTICAL FORMULATION COMPRISING ONE OR MORE FUMARIC ACID ESTERS IN AN EROSION MATRIX | BIOGEN SWISS MFG GMBH (CH) | 2022-03-17 | — | — | US | claimed |
| US-11229619-B2 | Controlled release pharmaceutical compositions comprising a fumaric acid ester | BIOGEN SWISS MANUFACTURING GMBH (CH) | 2022-01-25 | — | — | US | claimed |
| US-20190201368-A1 | CONTROLLED RELEASE PHARMACEUTICAL COMPOSITIONS COMPRISING A FUMARIC ACID ESTER | BIOGEN SWISS MANUFACTURING GMBH (CH) | 2019-07-04 | — | — | US | claimed |
| US-20190117613-A1 | CONTROLLED RELEASE PHARMACEUTICAL COMPOSITIONS COMPRISING A FUMARIC ACID ESTER | BIOGEN SWISS MANUFACTURING GMBH (CH) | 2019-04-25 | — | — | US | claimed |
| US-20180325855-A1 | CONTROLLED RELEASE PHARMACEUTICAL COMPOSITIONS COMPRISING A FUMARIC ACID ESTER | FWP IP APS (DK) | 2018-11-15 | — | — | US | claimed |
| US-20180263947-A1 | CONTROLLED RELEASE PHARMACEUTICAL COMPOSITIONS COMPRISING A FUMARIC ACID ESTER | BIOGEN SWISS MANUFACTURING GMBH (CH) | 2018-09-20 | — | — | US | claimed |
| US-20180221284-A1 | PHARMACEUTICAL FORMULATION COMPRISING ONE OR MORE FUMARIC ACID ESTERS IN AN EROSION MATRIX | BIOGEN SWISS MANUFACTURING GMBH (CH) | 2018-08-09 | — | — | US | claimed |
| US-20180098957-A1 | CONTROLLED RELEASE PHARMACEUTICAL COMPOSITIONS COMPRISING A FUMARIC ACID ESTER | BIOGEN SWISS MANUFACTURING GMBH (CH) | 2018-04-12 | — | — | US | claimed |
| US-20180028483-A1 | CONTROLLED RELEASE PHARMACEUTICAL COMPOSITIONS COMPRISING A FUMARIC ACID ESTER | BIOGEN SWISS MANUFACTURING GMBH (CH) | 2018-02-01 | — | — | US | claimed |
| EP-2379063-A1 | PHARMACEUTICAL FORMULATION COMPRISING ONE OR MORE FUMARIC ACID ESTERS IN AN EROSION MATRIX | Forward Pharma A/S (DK) | 2011-10-26 | — | — | EP | claimed |
| EP-2379062-A1 | PHARMACEUTICAL COMPOSITION COMPRISING ONE OR MORE FUMARIC ACID ESTERS | Forward Pharma A/S (DK) | 2011-10-26 | — | — | EP | claimed |
| WO-2010079222-A1 | PHARMACEUTICAL FORMULATION COMPRISING ONE OR MORE FUMARIC ACID ESTERS IN AN EROSION MATRIX | FORWARD PHARMA A/S (DK) | 2010-07-15 | — | — | WO | claimed |
| WO-2010079221-A1 | PHARMACEUTICAL COMPOSITION COMPRISING ONE OR MORE FUMARIC ACID ESTERS | FORWARD PHARMA A/S (DK) | 2010-07-15 | — | — | WO | claimed |
| US-20090304790-A1 | CONTROLLED RELEASE PHARMACEUTICAL COMPOSITIONS COMPRISING A FUMARIC ACID ESTER | ADITECH PHARMA AB (SE) | 2009-12-10 | — | — | US | claimed |
| US-20080299196-A1 | Controlled Release Pharmaceutical Compositions Comprising a Fumaric Acid Ester | ADITECH PHARMA AB (SE) | 2008-12-04 | — | — | US | claimed |
| EP-1951206-A1 | CONTROLLED RELEASE PHARMACEUTICAL COMPOSITIONS COMPRISING A FUMARIC ACID ESTER | Aditech Pharma AB (SE) | 2008-08-06 | — | — | EP | claimed |
| EP-1799196-A2 | CONTROLLED RELEASE PHARMACEUTICAL COMPOSITIONS COMPRISING A FUMARIC ACID ESTER | Aditech Pharma AB (SE) | 2007-06-27 | — | — | EP | claimed |
| WO-2007042034-A1 | CONTROLLED RELEASE PHARMACEUTICAL COMPOSITIONS COMPRISING A FUMARIC ACID ESTER | ADITECH PHARMA AB (SE) | 2007-04-19 | — | — | WO | claimed |
| WO-2006037342-A2 | CONTROLLED RELEASE PHARMACEUTICAL COMPOSITIONS COMPRISING A FUMARIC ACID ESTER | ADITECH PHARMA AB (SE) | 2006-04-13 | — | — | WO | claimed |