Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | PTGES | O14684 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5555250 | 0.85 | PPARA (0.51) | PTGDR2MAPTALDH1A1PPARAHTT | |
| SCHEMBL2885186 | 0.84 | PTGDR2 (0.57) | PTGDR2MAPTPOLBALDH1A1PPARA | |
| SCHEMBL2000083 | 0.83 | PTGDR2 (0.67) | PTGDR2MAPTHTTHPGDKMT2A | |
| SCHEMBL27971306 | 0.79 | SMN1; SMN2 (0.51) | PTGDR2MAPTALDH1A1PPARAMAPK1 | |
| SCHEMBL1996701 | 0.79 | PTGDR2 (0.55) | PTGDR2MAPT | |
| SCHEMBL4816920 | 0.78 | PPARA (0.59) | PTGDR2POLBALDH1A1PPARAHTT | |
| SCHEMBL4812741 | 0.78 | SMN1; SMN2 (0.48) | PTGDR2ALDH1A1PPARAHTTSMN1; SMN2 | |
| SCHEMBL5550261 | 0.78 | SMN1; SMN2 (0.46) | PTGDR2MAPTPPARAMAPK1NPSR1 | |
| SCHEMBL21057144 | 0.77 | PPARA (0.50) | POLBALDH1A1PPARANPSR1SMN1; SMN2 | |
| SCHEMBL21057133 | 0.77 | SMN1; SMN2 (0.47) | PTGDR2PPARAHTTSMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1756039-A4 | COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | EMISPHERE TECH INC (US) | 2007-05-02 | — | — | EP | disclosed |
| EP-1756039-A2 | COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | Emisphere Technologies, Inc. (US) | 2007-02-28 | — | — | EP | disclosed |
| WO-2005112633-A2 | COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | EMISPHERE TECHNOLOGIES, INC. (US) | 2005-12-01 | — | — | WO | disclosed |