Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 2/20 | 0.55 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.55 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.55 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | NAMPT | P43490 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5388774 | 0.96 | MAPK13 (0.59) | MAPK13MAPK12MAPK11MAPK14ALDH1A1 | |
| SCHEMBL5560593 | 0.90 | MAPK14 (0.54) | MAPK13MAPK12MAPK11MAPK14CCNA2 | |
| SCHEMBL5554671 | 0.90 | MAPK13 (0.52) | MAPK13MAPK12MAPK11MAPK14CCNA2 | |
| SCHEMBL5401571 | 0.89 | MAPK13 (0.52) | MAPK13MAPK12MAPK11MAPK14ALDH1A1 | |
| SCHEMBL5393308 | 0.89 | MAPK13 (0.53) | MAPK13MAPK12MAPK11MAPK14ALDH1A1 | |
| SCHEMBL5560863 | 0.87 | MAPK13 (0.46) | MAPK13MAPK12MAPK11MAPK14ALDH1A1 | |
| SCHEMBL5393291 | 0.86 | MAPK13 (0.56) | MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL5394382 | 0.86 | MAPK13 (0.58) | MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL5559190 | 0.86 | MAPK13 (0.47) | MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL5393298 | 0.85 | MAPK13 (0.64) | MAPK13MAPK12MAPK11MAPK14CCNA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1658288-B1 | 2-AMINO-5-BENZOYLTHIAZOLE NPY ANTAGONISTS | HOFFMANN LA ROCHE (CH) | 2007-12-05 | — | — | EP | disclosed |