Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1D | P48730 | 5/20 | 0.48 |
| ▸ | GSK3A | P49840 | 5/20 | 0.48 |
| ▸ | GSK3B | P49841 | 5/20 | 0.48 |
| ▸ | DYRK1A | Q13627 | 5/20 | 0.48 |
| ▸ | AURKB | Q96GD4 | 4/20 | 0.48 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.48 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.48 |
| ▸ | CCNC | P24863 | 5/20 | 0.46 |
| ▸ | CDK8 | P49336 | 5/20 | 0.46 |
| ▸ | ICAM1 | P05362 | 12/20 | 0.46 |
| ▸ | SELE | P16581 | 12/20 | 0.46 |
| ▸ | VCAM1 | P19320 | 5/20 | 0.46 |
| ▸ | CDK1 | P06493 | 4/20 | 0.43 |
| ▸ | PIM1 | P11309 | 4/20 | 0.43 |
| ▸ | CDK2 | P24941 | 4/20 | 0.43 |
| ▸ | KDR | P35968 | 4/20 | 0.43 |
| ▸ | PLK1 | P53350 | 4/20 | 0.43 |
| ▸ | PLK3 | Q9H4B4 | 4/20 | 0.43 |
| ▸ | PRKACA | P17612 | 3/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL660155 | 0.85 | CSNK1D (0.63) | CSNK1DGSK3AGSK3BDYRK1AAURKB | |
| SCHEMBL30744198 | 0.85 | CSNK1D (0.63) | CSNK1DGSK3AGSK3BDYRK1AAURKB | |
| SCHEMBL7159801 | 0.84 | ICAM1 (0.62) | CSNK1DGSK3AGSK3BDYRK1AAURKB | |
| SCHEMBL29069419 | 0.83 | ICAM1 (0.43) | CSNK1DGSK3AGSK3BDYRK1AAURKB | |
| SCHEMBL30980406 | 0.83 | ICAM1 (0.43) | CSNK1DGSK3AGSK3BDYRK1AAURKB | |
| SCHEMBL7059753 | 0.82 | ICAM1 (0.44) | CSNK1DGSK3AGSK3BDYRK1AAURKB | |
| SCHEMBL7057688 | 0.82 | CCNC (0.44) | CSNK1DGSK3AGSK3BDYRK1AAURKB | |
| SCHEMBL7051775 | 0.79 | ICAM1 (0.50) | CSNK1DGSK3AGSK3BDYRK1AAURKB | |
| SCHEMBL660382 | 0.78 | GSK3A (0.60) | CSNK1DGSK3AGSK3BDYRK1AAURKB | |
| SCHEMBL29069393 | 0.76 | ICAM1 (0.69) | CSNK1DGSK3AGSK3BDYRK1AAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1753428-A2 | KINASE INHIBITORS AS THERAPEUTIC AGENTS | Abbott Laboratories (US) | 2007-02-21 | — | — | EP | disclosed |
| US-20060074102-A1 | Kinase inhibitors as therapeutic agents | ABBOTT LABORATORIES | 2006-04-06 | — | — | US | disclosed |
| WO-2005110410-A2 | KINASE INHIBITORS AS THERAPEUTIC AGENTS | ABBOTT LABORATORIES (US) | 2005-11-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060074102-A1 | Kinase inhibitors as therapeutic agents | ABL1, MAP3K19, MAP3K20 | CSNK1D 151/4885GSK3A 453/4885GSK3B 462/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.