Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 4/20 | 0.65 |
| ▸ | KDM1A | O60341 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | FOXM1 | Q08050 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11477736 | 0.94 | FOXM1 (0.65) | BCHEKDM1AKMT2AMEN1RAB9A | |
| SCHEMBL32677549 | 0.90 | CYP2C9 (0.64) | BCHEKDM1AKMT2AMEN1RAB9A | |
| SCHEMBL7219006 | 0.86 | MEN1 (0.75) | BCHEKMT2AMEN1RAB9AKDM4E | |
| Carbamic Acid SCHEMBL5481170 | 0.86 | KDM4E (0.65) | BCHEKDM1AKMT2AMEN1RAB9A | |
| SCHEMBL18952101 | 0.84 | BCHE (0.61) | BCHEKMT2AMEN1FOXM1KDM4E | |
| SCHEMBL6701121 | 0.82 | KDM1A (0.46) | BCHEKDM1AKMT2AMEN1RAB9A | |
| SCHEMBL6268294 | 0.82 | KDM1A (0.46) | BCHEKDM1AKMT2AMEN1RAB9A | |
| SCHEMBL6268288 | 0.82 | KDM1A (0.46) | BCHEKDM1AKMT2AMEN1RAB9A | |
| SCHEMBL663239 | 0.82 | GRIN2B (0.74) | BCHEKMT2AMEN1RAB9AGRIN2B | |
| Hydrochloric Acid SCHEMBL2550113 | 0.80 | MEN1 (0.78) | BCHEKMT2AMEN1RAB9AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1761509-A2 | SUBSTITUTED CYCLOALKYL DERIVATIVES FOR THE TREATMENT OF RESPIRATORY DISEASES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-03-14 | — | — | EP | disclosed |
| WO-2005111002-A2 | SUBSTITUTED CYCLOALKYL DERIVATIVES FOR USE IN THE TREATMENT OF RESPIRATORY DISEASES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-11-24 | — | — | WO | disclosed |