Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL392278 | 0.86 | MAP2K1 (1.00) | MAP2K1MAP2K2 | |
| SCHEMBL393974 | 0.83 | MAP2K1 (0.76) | MAP2K1MAP2K2 | |
| SCHEMBL391336 | 0.79 | MAP2K1 (1.00) | MAP2K1MAP2K2 | |
| SCHEMBL5562628 | 0.79 | MAP2K1 (0.62) | MAP2K1MAP2K2 | |
| SCHEMBL1022468 | 0.77 | MAP2K1 (0.83) | MAP2K1MAP2K2 | |
| SCHEMBL5560204 | 0.76 | MAP2K1 (0.66) | MAP2K1MAP2K2 | |
| SCHEMBL392380 | 0.76 | MAP2K1 (0.65) | MAP2K1MAP2K2 | |
| SCHEMBL5497932 | 0.76 | MAP2K1 (0.86) | MAP2K1MAP2K2 | |
| SCHEMBL388709 | 0.75 | MAP2K1 (0.80) | MAP2K1MAP2K2 | |
| SCHEMBL393767 | 0.75 | MAP2K1 (1.00) | MAP2K1MAP2K2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1682138-A4 | HETEROCYCLIC INHIBITORS OF MEK AND METHODS OF USE THEREOF | ARRAY BIOPHARMA INC (US) | 2007-01-24 | — | — | EP | disclosed |
| EP-1682138-A2 | HETEROCYCLIC INHIBITORS OF MEK AND METHODS OF USE THEREOF | Array Biopharma, Inc. (US) | 2006-07-26 | — | — | EP | disclosed |
| WO-2005051301-A2 | HETEROCYCLIC INHIBITORS OF MEK AND METHODS OF USE THEREOF | ARRAY BIOPHARMA INC. (US) | 2005-06-09 | — | — | WO | disclosed |