Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | MITF | O75030 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 15/20 | 0.48 |
| ▸ | PPARA | Q07869 | 14/20 | 0.48 |
| ▸ | PPARD | Q03181 | 9/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.48 |
| ▸ | BCL2 | P10415 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5550996 | 0.91 | PPARG (0.49) | NPC1MITFLMNATP53RAB9A | |
| SCHEMBL14437954 | 0.89 | PPARG (0.45) | NPC1MITFLMNATP53RAB9A | |
| SCHEMBL5550668 | 0.88 | PPARG (0.52) | NPC1MITFLMNATP53RAB9A | |
| SCHEMBL5556252 | 0.88 | PPARA (0.50) | PPARGPPARAPPARD | |
| SCHEMBL5555645 | 0.88 | PPARG (0.46) | NPC1RAB9APPARGPPARAPPARD | |
| SCHEMBL5556228 | 0.83 | PPARG (0.46) | PPARGPPARAPPARD | |
| SCHEMBL5551017 | 0.82 | PPARG (0.47) | PPARGPPARAPPARD | |
| SCHEMBL5556307 | 0.80 | PPARG (0.57) | PPARGPPARAPPARD | |
| SCHEMBL4335117 | 0.79 | PPARG (0.52) | NPC1MITFLMNARAB9APPARG | |
| SCHEMBL5556243 | 0.78 | PPARA (0.45) | NPC1LMNARAB9ASMN1; SMN2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7253178-B2 | Carboxylic acids | EISAI CO., LTD. (JP) | 2007-08-07 | — | — | US | disclosed |
| US-7253178-B2 | Carboxylic acids | EISAI CO., LTD. (JP) | 2007-08-07 | — | — | US | disclosed |
| US-7253178-B2 | Carboxylic acids | EISAI CO., LTD. (JP) | 2007-08-07 | — | — | US | disclosed |
| US-20040116708-A1 | Insulin sensitizers; antidiabetic agents, antiinflammatory agents; inflammatory bowel disorders | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2004-06-17 | — | — | US | disclosed |
| EP-1375484-A1 | CARBOXYLIC ACIDS | Eisai Co., Ltd. (JP) | 2004-01-02 | — | — | EP | disclosed |