Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.53 |
| ▸ | HRH1 | P35367 | 1/20 | 0.53 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14365317 | 1.00 | CHRM1 (0.53) | CHRM1HRH1PAK1 | |
| SCHEMBL5558265 | 0.94 | CHRM1 (0.49) | CHRM1HRH1PAK1 | |
| SCHEMBL14365255 | 0.94 | CHRM1 (0.49) | CHRM1HRH1PAK1 | |
| SCHEMBL14156708 | 0.90 | CHRM1 (0.53) | CHRM1HRH1PAK1 | |
| SCHEMBL14511275 | 0.88 | CHRM1 (0.56) | CHRM1HRH1PAK1 | |
| SCHEMBL4836859 | 0.88 | CHRM1 (0.52) | CHRM1HRH1PAK1 | |
| SCHEMBL4836862 | 0.88 | CHRM1 (0.52) | CHRM1HRH1PAK1 | |
| Hydrochloric Acid SCHEMBL4837106 | 0.87 | CHRM1 (0.51) | CHRM1HRH1PAK1 | |
| Hydrochloric Acid SCHEMBL4837117 | 0.87 | CHRM1 (0.51) | CHRM1HRH1PAK1 | |
| Hydrochloric Acid SCHEMBL4837113 | 0.87 | CHRM1 (0.51) | CHRM1HRH1PAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1492794-B1 | PIPERAZINE SUBSTITUTED ARYL BENZODIAZEPINES AND THEIR USE AS DOPAMINE RECEPTOR ANTAGONISTS FOR THE TREATMENT OF PSYCHOTIC DISORDERS | LILLY CO ELI (US) | 2007-12-12 | — | — | EP | disclosed |