Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 9/20 | 0.62 |
| ▸ | BLM | P54132 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | VCP | P55072 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | PNP | P00491 | 2/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | EDNRA | P25101 | 1/20 | 0.54 |
| ▸ | HTR2A | P28223 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | HBB | P68871 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | TK1 | P04183 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10770108 | 0.88 | HPRT1 (0.60) | HPRT1BLMMEN1KMT2AALDH1A1 | |
| SCHEMBL25611147 | 0.85 | BLM (0.55) | HPRT1BLMMEN1KMT2AALDH1A1 | |
| SCHEMBL24263987 | 0.84 | BLM (0.56) | HPRT1BLMMEN1KMT2AALDH1A1 | |
| SCHEMBL5168886 | 0.83 | MEN1 (0.57) | HPRT1BLMMEN1KMT2AALDH1A1 | |
| SCHEMBL25613199 | 0.82 | HPRT1 (0.53) | HPRT1BLMMEN1KMT2AALDH1A1 | |
| SCHEMBL21311340 | 0.81 | HPRT1 (0.61) | HPRT1BLMMEN1KMT2AALDH1A1 | |
| SCHEMBL22398914 | 0.81 | HPRT1 (0.49) | HPRT1BLMMEN1KMT2AALDH1A1 | |
| SCHEMBL12016843 | 0.81 | HPRT1 (0.49) | HPRT1BLMMEN1KMT2AALDH1A1 | |
| SCHEMBL5166552 | 0.80 | MEN1 (0.54) | HPRT1BLMMEN1KMT2AALDH1A1 | |
| SCHEMBL25611139 | 0.80 | PNP (0.53) | HPRT1BLMMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8324381-B2 | Preparation of ester of purine derivatives | CIPLA LIMITED (IN) | 2012-12-04 | — | — | US | disclosed |
| US-20070225305-A1 | Preparation of ester of purine derivatives | CIPLA LIMITED (IN) | 2007-09-27 | — | — | US | disclosed |
| EP-1837336-A1 | Preparation of valganciclovir | Cipla Ltd. (IN) | 2007-09-26 | — | — | EP | disclosed |
| WO-2005092891-A2 | PREPARATION OF ESTERS OF GANCICLOVIR | RANBAXY LABORATORIES LIMITED (IN) | 2005-10-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070225305-A1 | Preparation of ester of purine derivatives | PNP, TYMP, MTAP | HPRT1 17/4885BLM 1230/4885MEN1 3875/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.