Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | PPIA | P62937 | 7/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.40 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.40 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5464407 | 0.83 | KMT2A (0.53) | KMT2AMAPTMEN1LMNATSHR | |
| SCHEMBL11483016 | 0.79 | KMT2A (0.50) | KMT2AMAPTMEN1LMNATSHR | |
| SCHEMBL5525117 | 0.79 | KMT2A (0.59) | KMT2AMAPTMEN1LMNATSHR | |
| SCHEMBL11483849 | 0.75 | KMT2A (0.50) | KMT2AMAPTMEN1LMNATSHR | |
| SCHEMBL29273709 | 0.74 | MAPT (0.65) | KMT2AMAPTMEN1LMNATSHR | |
| Iodide SCHEMBL11495519 | 0.73 | KMT2A (0.49) | KMT2AMAPTMEN1LMNATSHR | |
| SCHEMBL1007576 | 0.72 | MAPT (0.62) | KMT2AMAPTMEN1LMNATSHR | |
| SCHEMBL1567605 | 0.72 | KMT2A (0.61) | KMT2AMAPTMEN1LMNATSHR | |
| SCHEMBL144326 | 0.71 | KMT2A (0.65) | KMT2AMAPTMEN1LMNATSHR | |
| SCHEMBL7528270 | 0.71 | MAPT (0.65) | KMT2AMAPTMEN1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1689705-A4 | FUSED RING DICATIONIC ANTI-PROTOZOAN AGENTS AND THEIR PRODRUGS | UNIV NORTH CAROLINA (US) | 2007-08-29 | — | — | EP | disclosed |
| EP-1689705-A2 | FUSED RING DICATIONIC ANTI-PROTOZOAN AGENTS AND THEIR PRODRUGS | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2006-08-16 | — | — | EP | disclosed |
| WO-2005051296-A2 | FUSED RING DICATIONIC ANTI-PROTOZOAN AGENTS AND THEIR PRODRUGS | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2005-06-09 | — | — | WO | disclosed |