⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12143358 | 1.00 | MEN1 (0.35) | — | |
| SCHEMBL9955330 | 0.86 | MEN1 (0.39) | — | |
| SCHEMBL1154318 | 0.86 | MEN1 (0.39) | — | |
| SCHEMBL559048 | 0.86 | MEN1 (0.39) | — | |
| SCHEMBL525920 | 0.83 | — | — | |
| SCHEMBL16328524 | 0.79 | MEN1 (0.31) | — | |
| SCHEMBL26003552 | 0.79 | MEN1 (0.31) | — | |
| SCHEMBL11885390 | 0.76 | ODC1 (0.41) | — | |
| SCHEMBL667646 | 0.76 | — | — | |
| SCHEMBL10076924 | 0.76 | ODC1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110124556-A1 | Insulin and IGF-1 Receptor Agonists and Antagonists | NOVO NORDISK A/S (DK) | 2011-05-26 | — | — | US | disclosed |
| EP-1799267-A2 | CONJUGATES OF HYDROXYALKYL STARCH AND A PROTEIN | Fresenius Kabi Deutschland GmbH (DE) | 2007-06-27 | — | — | EP | disclosed |
| WO-2005092390-A2 | CONJUGATES OF HYDROXYALKYL STARCH AND A PROTEIN | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2005-10-06 | — | — | WO | disclosed |