Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 2/20 | 0.51 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.51 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5404354 | 0.96 | MAPK13 (0.55) | MAPK13MAPK12MAPK11MAPK14CYP19A1 | |
| SCHEMBL5560310 | 0.94 | MAPK13 (0.54) | MAPK13MAPK12MAPK11MAPK14CYP19A1 | |
| SCHEMBL5394404 | 0.90 | MAPK13 (0.58) | MAPK13MAPK12MAPK11MAPK14CYP19A1 | |
| SCHEMBL5400916 | 0.88 | MAPK13 (0.49) | MAPK13MAPK12MAPK11MAPK14ALDH1A1 | |
| SCHEMBL5559458 | 0.87 | MAPK13 (0.47) | MAPK13MAPK12MAPK11MAPK14AURKA | |
| SCHEMBL5559010 | 0.86 | MAPK13 (0.43) | MAPK13MAPK12MAPK11MAPK14AURKA | |
| SCHEMBL5398153 | 0.86 | MAPK13 (0.51) | MAPK13MAPK12MAPK11MAPK14CYP19A1 | |
| SCHEMBL5401571 | 0.84 | MAPK13 (0.52) | MAPK13MAPK12MAPK11MAPK14CYP19A1 | |
| SCHEMBL5554593 | 0.84 | MAPK13 (0.44) | MAPK13MAPK12MAPK11MAPK14SMN1; SMN2 | |
| SCHEMBL5554186 | 0.84 | MAPK13 (0.44) | MAPK13MAPK12MAPK11MAPK14AURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1658288-B1 | 2-AMINO-5-BENZOYLTHIAZOLE NPY ANTAGONISTS | HOFFMANN LA ROCHE (CH) | 2007-12-05 | — | — | EP | disclosed |