Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 5/20 | 0.51 |
| ▸ | GSK3A | P49840 | 3/20 | 0.51 |
| ▸ | CDK1 | P06493 | 2/20 | 0.51 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.51 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.51 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.51 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4396211 | 0.79 | GSK3B (0.75) | GSK3BGSK3ACDK1CCNB2CCNB1 | |
| Hydrochloric Acid SCHEMBL5093397 | 0.79 | GSK3B (0.74) | GSK3BGSK3ACDK1CCNB2CCNB1 | |
| SCHEMBL7022640 | 0.78 | GSK3B (0.54) | GSK3BGSK3ACDK1CCNB2CCNB1 | |
| SCHEMBL5082585 | 0.78 | GSK3B (0.58) | GSK3BGSK3ACDK1CCNB2CCNB1 | |
| SCHEMBL5558006 | 0.77 | GSK3B (0.53) | GSK3BGSK3ACDK1CCNB2CCNB1 | |
| SCHEMBL7851212 | 0.75 | GSK3B (0.55) | GSK3BGSK3ACDK1CCNB2CCNB1 | |
| SCHEMBL4399102 | 0.75 | GSK3B (0.67) | GSK3BGSK3ACDK1CCNB2CCNB1 | |
| SCHEMBL4399097 | 0.75 | GSK3B (0.64) | GSK3BGSK3ACDK1CCNB2CCNB1 | |
| SCHEMBL7022318 | 0.74 | GSK3B (0.69) | GSK3BGSK3ACDK1CCNB2CCNB1 | |
| SCHEMBL7019626 | 0.74 | GSK3B (0.54) | GSK3BGSK3ACDK1CCNB2CCNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1490093-A4 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF ISCHEMIA | NOVARTIS VACCINES & DIAGNOSTIC (US) | 2007-04-11 | — | — | EP | disclosed |
| EP-1490093-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF ISCHEMIA | CHIRON CORPORATION (US) | 2004-12-29 | — | — | EP | disclosed |
| WO-2003074072-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF ISCHEMIA | CHIRON CORPORATION (US) | 2003-09-12 | — | — | WO | disclosed |