Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 2/20 | 0.51 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.51 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.51 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5559823 | 0.92 | MAPK13 (0.46) | MAPK13MAPK12MAPK11MAPK14CCNA2 | |
| SCHEMBL5554634 | 0.91 | MAPK13 (0.50) | MAPK13MAPK12MAPK11MAPK14CCNA2 | |
| SCHEMBL5559229 | 0.91 | MAPK13 (0.49) | MAPK13MAPK12MAPK11MAPK14CCNA2 | |
| SCHEMBL5559000 | 0.90 | MAPK13 (0.47) | MAPK13MAPK12MAPK11MAPK14MEN1 | |
| SCHEMBL5554708 | 0.90 | MAPK13 (0.49) | MAPK13MAPK12MAPK11MAPK14MEN1 | |
| SCHEMBL5559225 | 0.89 | MAPK13 (0.43) | MAPK13MAPK12MAPK11MAPK14CCNA2 | |
| SCHEMBL5393298 | 0.88 | MAPK13 (0.64) | MAPK13MAPK12MAPK11MAPK14CCNA2 | |
| SCHEMBL5554647 | 0.88 | MAPK13 (0.42) | MAPK13MAPK12MAPK11MAPK14CCNA2 | |
| SCHEMBL5555031 | 0.86 | MEN1 (0.42) | MAPK13MAPK12MAPK11MAPK14MEN1 | |
| SCHEMBL5559998 | 0.86 | MAPK13 (0.43) | MAPK13MAPK12MAPK11MAPK14CCNA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1658288-B1 | 2-AMINO-5-BENZOYLTHIAZOLE NPY ANTAGONISTS | HOFFMANN LA ROCHE (CH) | 2007-12-05 | — | — | EP | disclosed |