Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 8/20 | 0.49 |
| ▸ | MAPK12 | P53778 | 8/20 | 0.49 |
| ▸ | MAPK11 | Q15759 | 8/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 8/20 | 0.49 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5401581 | 0.88 | MAPK13 (0.46) | MAPK13MAPK12MAPK11MAPK14CCNA2 | |
| SCHEMBL5400048 | 0.85 | MAPK14 (0.64) | MAPK13MAPK12MAPK11MAPK14CCNA2 | |
| SCHEMBL5393306 | 0.85 | MAPK13 (0.61) | MAPK13MAPK12MAPK11MAPK14CCNA2 | |
| SCHEMBL5401082 | 0.85 | MAPK13 (0.54) | MAPK13MAPK12MAPK11MAPK14RAB9A | |
| SCHEMBL5393298 | 0.84 | MAPK13 (0.64) | MAPK13MAPK12MAPK11MAPK14CCNA2 | |
| SCHEMBL27645729 | 0.84 | MAPK13 (0.45) | MAPK13MAPK12MAPK11MAPK14CCNA2 | |
| SCHEMBL5395181 | 0.83 | MAPK13 (0.52) | MAPK13MAPK12MAPK11MAPK14CCNA2 | |
| SCHEMBL5400927 | 0.83 | MAPK13 (0.53) | MAPK13MAPK12MAPK11MAPK14RAB9A | |
| SCHEMBL5404046 | 0.82 | MAPK13 (0.44) | MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL5409011 | 0.82 | MAPK13 (0.53) | MAPK13MAPK12MAPK11MAPK14RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1658288-B1 | 2-AMINO-5-BENZOYLTHIAZOLE NPY ANTAGONISTS | HOFFMANN LA ROCHE (CH) | 2007-12-05 | — | — | EP | claimed |