Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 1/20 | 0.66 |
| ▸ | MEN1 | O00255 | 18/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 13/20 | 0.49 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1604937 | 0.91 | HTR2B (0.73) | HTR2BMEN1KMT2A | |
| Prx-08066 Free Base SCHEMBL29390783 | 0.79 | HTR2B (1.00) | HTR2BMEN1KMT2APIK3CD | |
| Prx-08066 Free Base SCHEMBL31237398 | 0.79 | HTR2B (1.00) | HTR2BMEN1KMT2APIK3CD | |
| Prx-08066 Free Base SCHEMBL1604039 | 0.79 | HTR2B (1.00) | HTR2BMEN1KMT2APIK3CD | |
| SCHEMBL1604017 | 0.79 | HTR2B (0.67) | HTR2BMEN1KMT2A | |
| SCHEMBL1604942 | 0.79 | HTR2B (0.72) | HTR2BMEN1KMT2A | |
| SCHEMBL14703360 | 0.74 | HTR2B (0.46) | HTR2BMEN1KMT2APIK3CD | |
| SCHEMBL14703321 | 0.74 | HTR2B (0.46) | HTR2BMEN1KMT2APIK3CD | |
| Prx-08066 Free Base SCHEMBL29520105 | 0.74 | HTR2B (0.86) | HTR2BMEN1KMT2APIK3CD | |
| SCHEMBL1604143 | 0.73 | HTR2B (0.69) | HTR2BMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1797099-A1 | PIPERIDINYLAMINO-THIENO[2,3-D] PYRIMIDINE COMPOUNDS | Epix Delaware, Inc. (US) | 2007-06-20 | — | — | EP | disclosed |
| WO-2006034511-A1 | PIPERIDINYLAMINO-THIENO[2,3-D] PYRIMIDINE COMPOUNDS | EPIX DELAWARE, INC. (US) | 2006-03-30 | — | — | WO | disclosed |