SCHEMBL5564580

SCHEMBL5564580

C=CC1=C(C(=O)O)N2C(=O)[C@@H](NC(=O)C(NO)c3csc(N)n3)[C@@H]2SC1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 5/20 0.77
HPGD P15428 1/20 0.77
MAPT P10636 3/20 0.63
ABCC4 O15439 1/20 0.63
CNR1 P21554 1/20 0.63
CTDSP1 Q9GZU7 1/20 0.63
APAF1 O14727 2/20 0.58
LMNA P02545 1/20 0.58
TSHR P16473 1/20 0.58
APEX1 P27695 1/20 0.58
PLCG1 P19174 1/20 0.58
ABCC2 Q92887 1/20 0.58
SIRT5 Q9NXA8 1/20 0.58
L3MBTL1 Q9Y468 1/20 0.58
PSMD14 O00487 1/20 0.58
MMP2 P08253 1/20 0.58
POLB P06746 1/20 0.52
PKM P14618 1/20 0.52
HTT P42858 1/20 0.52
DUSP3 P51452 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17430786 1.00 TDP1 (0.77) TDP1HPGDMAPTABCC4CNR1
SCHEMBL13287328 0.92 TDP1 (0.76) TDP1HPGDMAPTABCC4CNR1
SCHEMBL9481543 0.90 TDP1 (0.81) TDP1HPGDMAPTABCC4CNR1
SCHEMBL10818943 0.90 TDP1 (0.73) TDP1HPGDMAPTABCC4CNR1
SCHEMBL10818952 0.90 TDP1 (0.73) TDP1HPGDMAPTABCC4CNR1
SCHEMBL13287289 0.90 TDP1 (0.70) TDP1HPGDMAPTABCC4CNR1
SCHEMBL11133665 0.90 TDP1 (0.85) TDP1HPGDMAPTABCC4CNR1
SCHEMBL9480984 0.90 TDP1 (0.85) TDP1HPGDMAPTABCC4CNR1
SCHEMBL9482997 0.82 TDP1 (0.68) TDP1HPGDMAPTABCC4CNR1
SCHEMBL10891854 0.81 TDP1 (0.67) TDP1HPGDMAPTABCC4CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7157576-B2 Crystalline acid salts of cefdinir and process for preparing cefdinir using same HANMI PHARM. CO., LTD. (KR) 2007-01-02 US disclosed
EP-1392703-A4 CRYSTALLINE ACID SALTS OF CEFDINIR AND PROCESS FOR PREPARING CEFDINIR USING SAME HANMI PHARM IND CO LTD (KR) 2004-10-27 EP disclosed
EP-1392703-A1 CRYSTALLINE ACID SALTS OF CEFDINIR AND PROCESS FOR PREPARING CEFDINIR USING SAME Hanmi Pharm. Co., Ltd. (KR) 2004-03-03 EP disclosed
WO-2002098884-A1 CRYSTALLINE ACID SALTS OF CEFDINIR AND PROCESS FOR PREPARING CEFDINIR USING SAME HANMI PHARM. CO., LTD. (KR) 2002-12-12 WO disclosed