Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | GGPS1 | O95749 | 6/20 | 0.37 |
| ▸ | FDPS | P14324 | 9/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | CPT2 | P23786 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.34 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9517663 | 1.00 | TSHR (0.40) | TSHRTHRBGGPS1FDPSFFAR1 | |
| SCHEMBL28927993 | 1.00 | TSHR (0.40) | TSHRTHRBGGPS1FDPSFFAR1 | |
| SCHEMBL11146567 | 1.00 | TSHR (0.40) | TSHRTHRBGGPS1FDPSFFAR1 | |
| SCHEMBL25384575 | 1.00 | TSHR (0.40) | TSHRTHRBGGPS1FDPSFFAR1 | |
| SCHEMBL25384828 | 1.00 | TSHR (0.40) | TSHRTHRBGGPS1FDPSFFAR1 | |
| SCHEMBL25384437 | 1.00 | TSHR (0.40) | TSHRTHRBGGPS1FDPSFFAR1 | |
| SCHEMBL25385601 | 1.00 | TSHR (0.40) | TSHRTHRBGGPS1FDPSFFAR1 | |
| SCHEMBL25386266 | 1.00 | TSHR (0.40) | TSHRTHRBGGPS1FDPSFFAR1 | |
| SCHEMBL5462951 | 1.00 | TSHR (0.40) | TSHRTHRBGGPS1FDPSFFAR1 | |
| SCHEMBL27476664 | 1.00 | TSHR (0.40) | TSHRTHRBGGPS1FDPSFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1751154-A1 | 5-SUBSTITUTED 1-PHENYL-1,5-DIHYDRO-PYRIDO[3,2-B] INDOL-2-ONES AND ANALOGS AS ANTI-VIRALS | Tibotec Pharmaceuticals Ltd. (IE) | 2007-02-14 | — | — | EP | disclosed |
| WO-2005111034-A1 | 5-SUBSTITUTED 1-PHENYL-1,5-DIHYDRO-PYRIDO’3,2-B! INDOL-2-ONES AND ANALOGS AS ANTI-VIRALS | TIBOTEC PHARMACEUTICALS LTD. (IE) | 2005-11-24 | — | — | WO | disclosed |