Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK9 | P45984 | 1/20 | 0.54 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | USP5 | P45974 | 1/20 | 0.39 |
| ▸ | TGM2 | P21980 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | BCL2 | P10415 | 1/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2424569 | 0.94 | MAPK9 (0.56) | MAPK9MAPK10MEN1KMT2ALMNA | |
| SCHEMBL1518747 | 0.91 | MAPK9 (0.56) | MAPK9MAPK10MEN1KMT2ALMNA | |
| SCHEMBL2422037 | 0.89 | MAPK9 (0.59) | MAPK9MAPK10MEN1KMT2ALMNA | |
| SCHEMBL2423120 | 0.89 | MAPK9 (0.57) | MAPK9MAPK10MEN1KMT2ALMNA | |
| SCHEMBL2423342 | 0.88 | MAPK9 (0.54) | MAPK9MAPK10MEN1KMT2ALMNA | |
| SCHEMBL1518964 | 0.88 | MAPK9 (0.54) | MAPK9MAPK10MEN1KMT2ALMNA | |
| SCHEMBL7442031 | 0.88 | MAPK9 (0.50) | MAPK9MAPK10MEN1KMT2ALMNA | |
| SCHEMBL2420821 | 0.87 | MAPK9 (0.56) | MAPK9MAPK10MEN1KMT2ALMNA | |
| SCHEMBL2421590 | 0.87 | MAPK9 (0.56) | MAPK9MAPK10MEN1KMT2ALMNA | |
| SCHEMBL6433119 | 0.87 | MAPK9 (0.57) | MAPK9MAPK10MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1850846-A1 | COMPOSITION COMPRISING A JNK INHIBITOR AND CYCLOSPORIN | Laboratoires Serono SA (CH) | 2007-11-07 | — | — | EP | disclosed |
| WO-2005097116-A1 | COMPOSITION COMPRISING A JNK INHIBITOR AND CYCLOSPORIN | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2005-10-20 | — | — | WO | disclosed |