⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL809080 | 0.70 | — | — | |
| SCHEMBL688566 | 0.70 | — | — | |
| SCHEMBL10600007 | 0.70 | — | — | |
| SCHEMBL809089 | 0.70 | — | — | |
| SCHEMBL1726945 | 0.67 | — | — | |
| SCHEMBL124775 | 0.67 | — | — | |
| SCHEMBL830469 | 0.67 | — | — | |
| SCHEMBL122037 | 0.65 | — | — | |
| SCHEMBL11235276 | 0.64 | — | — | |
| Glyoxylate SCHEMBL1518069 | 0.63 | TSHR (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105658639-A | Alkynyl alcohols and methods of use | 豪夫迈·罗氏有限公司 | 2016-06-08 | — | — | CN | disclosed |
| CN-105339368-A | 3-aryl-substituted imidazo[1,2-a]pyridines and the use thereof | Bayer Pharma AG | 2016-02-17 | — | — | CN | disclosed |
| CN-103508930-B | Two (aminodithioformic acid)-1,3-propylene diester compounds and synthetic method, pharmaceutical composition and purposes | PEKING UNIVERSITY (CN) | 2016-01-27 | — | — | CN | disclosed |
| CN-104981472-A | Heteroaromatic compounds and their use as dopamine d1 ligands | PFIZER | 2015-10-14 | — | — | CN | disclosed |
| CN-104981470-A | Amino-substituted imidazo[1,2-a]pyridinecarboxamides and their use | Bayer Pharma AG | 2015-10-14 | — | — | CN | disclosed |
| CN-104955823-A | Carboxy-substituted imidazo [1,2-a ] pyridinecarboxamides and their use as stimulators of soluble guanylate cyclase | Bayer Pharma AG | 2015-09-30 | — | — | CN | disclosed |
| CN-104918945-A | Tricyclic fused thiophene derivatives as JAK inhibitors | INCYTE CORP | 2015-09-16 | — | — | CN | disclosed |
| CN-104781258-A | Hydroxy-substituted imidazo [1,2-a ] pyridinecarboxamides and their use as soluble guanylate cyclase stimulators | Bayer Pharma AG | 2015-07-15 | — | — | CN | disclosed |
| CN-104619709-A | Imidazopyridine derivatives as modulators of TNF activity | UCB PHARMA SA | 2015-05-13 | — | — | CN | disclosed |
| CN-104470924-A | Imidazopyrazine derivatives as modulators of tnf activity | UCB PHARMA SA | 2015-03-25 | — | — | CN | disclosed |
| CN-102395585-A | Heteroaryls and their use as pi3k inhibitors | MILLENNIUM PHARM INC | 2012-03-28 | — | — | CN | disclosed |
| EP-1480976-B1 | THIAZOLE DERIVATIVES AS NPY RECEPTOR ANTAGONISTS | HOFFMANN LA ROCHE (CH) | 2007-09-19 | — | — | EP | disclosed |
| EP-1480976-A1 | THIAZOLE DERIVATIVES AS NPY RECEPTOR ANTAGONISTS | F.HOFFMANN-LA ROCHE AG (CH) | 2004-12-01 | — | — | EP | disclosed |
| CN-1170822-C | Imidazole compounds and pharmaceutical use thereof | ����ҩƷ��ҵ��ʽ���� | 2004-10-13 | — | — | CN | disclosed |
| US-6686381-B2 | COMPOUNDS THAT ANTAGONIZE NEUROPEPTIDE Y AT THE Y5 RECEPTOR SUBTYPE REPRESENT AN APPROACH TO THE TREATMENT OF EATING DISORDERS SUCH AS OBESITY AND HYPERPHAGIA | HOFFMANN-LA ROCHE INC. | 2004-02-03 | — | — | US | disclosed |
| US-20030225141-A1 | THIAZOLE DERIVATIVES | HOFFMANN-LA ROCHE INC. | 2003-12-04 | — | — | US | disclosed |
| WO-2003072577-A1 | THIAZOLE DERIVATIVES AS NPY RECEPTOR ANTAGONISTS | F.HOFFMANN-LA ROCHE AG (CH) | 2003-09-04 | — | — | WO | disclosed |
| CN-1335837-A | Imidazole compounds and medicinal use thereof | FUJISAWA PHARMACEUTICAL CO (JP) | 2002-02-13 | — | — | CN | disclosed |
| CN-1268942-A | Sulfonamide compounds and medicinal use thereof | FUJISAWA PHARMACEUTICAL CO (JP) | 2000-10-04 | — | — | CN | disclosed |
| CN-1020608-C | Preparation of 5-(6-imidazo [1,2-a] pyridyl) pyridine derivative | EISAI CO LTD (JP) | 1993-05-12 | — | — | CN | disclosed |