Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP2 | Q8WXD0 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | GHSR | Q92847 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | UGCG | Q16739 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.34 |
| ▸ | WNT3A | P56704 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL557122 | 0.79 | SMN1; SMN2 (0.36) | RAB9AMAPT | |
| SCHEMBL16069988 | 0.75 | CYP3A4 (0.43) | KDM4ENPC1RAB9APOLBCTDSP1 | |
| SCHEMBL16069991 | 0.75 | CYP3A4 (0.43) | KDM4ENPC1RAB9APOLBCTDSP1 | |
| SCHEMBL556708 | 0.73 | KMT2A (0.39) | KDM4ENPC1RAB9APOLBCTDSP1 | |
| SCHEMBL10107742 | 0.64 | ALDH2 (0.77) | ALDH2KDM4EPOLBTDP1MAPT | |
| SCHEMBL557011 | 0.63 | TSHR (0.41) | NPC1RAB9APOLBTDP1MAPT | |
| SCHEMBL16069990 | 0.61 | KDM4E (0.42) | RXFP1KDM4ENPC1RAB9APOLB | |
| SCHEMBL29216848 | 0.59 | CYP3A4 (0.60) | NPC1RAB9ATDP1CYP3A4 | |
| SCHEMBL28259740 | 0.59 | ALDH2 (0.82) | ALDH2KDM4ERECQLGHSRPOLB | |
| SCHEMBL2346138 | 0.58 | CYP3A4 (0.63) | NPC1RAB9ATDP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120035114-A1 | INHIBITORS OF STAT3 AND USES THEREOF | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2012-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120035114-A1 | INHIBITORS OF STAT3 AND USES THEREOF | STAT3, JAK2, STAT6 | RXFP2 2151/4885RXFP1 1909/4885ALDH2 3041/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.